Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264549 | 0.85 | ALDH1A1 (0.50) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL1010516 | 0.84 | TSHR (0.48) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL6382642 | 0.83 | CA1 (0.52) | RAB9ANPC1ALDH1A1HPGDCES2 | |
| SCHEMBL7324913 | 0.82 | CYP19A1 (0.49) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7324910 | 0.82 | CYP19A1 (0.49) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL9899633 | 0.81 | SMN1; SMN2 (0.47) | RAB9ANPC1MAPK1HTTMAPT | |
| SCHEMBL9899631 | 0.81 | SMN1; SMN2 (0.47) | RAB9ANPC1MAPK1HTTMAPT | |
| SCHEMBL3267872 | 0.80 | NPC1 (0.44) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL6555908 | 0.80 | CES2 (0.56) | RAB9AKMT2ANPC1SMN1; SMN2GAA | |
| SCHEMBL6555910 | 0.80 | CES2 (0.56) | RAB9AKMT2ANPC1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101341141-B | Photochromic indeno-fused naphthopyrans | 光学转变公司 | 2016-09-28 | — | — | CN | disclosed |
| EP-1966180-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2015-02-18 | — | — | EP | disclosed |
| EP-1963896-B1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL INC (US) | 2010-02-10 | — | — | EP | disclosed |
| US-7556751-B2 | Photochromic materials having electron-withdrawing substituents | TRANSITIONS OPTICAL, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-7527754-B2 | Photochromic indeno-fused naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 2009-05-05 | — | — | US | disclosed |
| EP-1966180-A1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1963896-A1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL, INC. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007078529-A1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007073462-A1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL, INC. (US) | 2007-06-28 | — | — | WO | disclosed |
| US-20070138448-A1 | Photochromic indeno-fused naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2007-06-21 | — | — | US | disclosed |
| US-20070138449-A1 | Photochromic materials having electron-withdrawing substituents | TRANSITIONS OPTICAL LIMITED (IE) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070138448-A1 | Photochromic indeno-fused naphthopyrans | INTS6, IPO4, NQO1 | RAB9A 4170/4885MEN1 4527/4885KMT2A 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.