Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688223 | 0.93 | KISS1R (0.35) | USP2HSD17B10MAPK1KISS1RALDH1A1 | |
| SCHEMBL32688427 | 0.92 | KISS1R (0.35) | USP2HSD17B10SMN1; SMN2MAPK1KISS1R | |
| SCHEMBL32688418 | 0.92 | HSD17B10 (0.40) | USP2HSD17B10SMN1; SMN2MAPK1KISS1R | |
| SCHEMBL32688425 | 0.90 | KISS1R (0.39) | HSP90AA1HSP90AB1KISS1RALDH1A1 | |
| SCHEMBL32688199 | 0.90 | HSD11B1 (0.36) | SMN1; SMN2MAPK1KISS1RALDH1A1HPGD | |
| SCHEMBL32688118 | 0.90 | CTSS (0.39) | MAPK1MAPT | |
| SCHEMBL32688472 | 0.89 | GRK6 (0.36) | SMN1; SMN2KISS1RALDH1A1HPGDKMT2A | |
| SCHEMBL32688310 | 0.88 | GRK6 (0.37) | HSD17B10SMN1; SMN2MAPK1KISS1RALDH1A1 | |
| SCHEMBL32688163 | 0.88 | KISS1R (0.39) | CYP1A2CYP2D6KISS1RTHRBHTT | |
| SCHEMBL32688018 | 0.82 | OTUD7B (0.40) | ALDH1A1HPGDL3MBTL1PIK3CDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | USP2 2048/4885CYP1A2 959/4885CYP2D6 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.