Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688111 | 0.88 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL8349147 | 0.71 | LOXL2 (0.46) | ALDH1A1SMN1; SMN2RAB9AMAPK1NPC1 | |
| SCHEMBL8506679 | 0.71 | ESR1 (0.39) | ALDH1A1SMN1; SMN2HTTMAPK1KDM4E | |
| SCHEMBL4220817 | 0.68 | TSHR (0.43) | ALDH1A1FABP4SMN1; SMN2PYCR1LMNA | |
| SCHEMBL32688167 | 0.68 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTRAB9AMAPK1 | |
| SCHEMBL6337118 | 0.68 | AOC3 (0.46) | — | |
| SCHEMBL9402366 | 0.67 | GLA (0.42) | ALDH1A1PIK3CASMN1; SMN2LMNAHTT | |
| SCHEMBL29336627 | 0.67 | BCL2A1 (0.56) | ALDH1A1SMN1; SMN2PYCR1HTT | |
| SCHEMBL795874 | 0.67 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2LMNARAB9ATSHR | |
| SCHEMBL32688122 | 0.66 | FABP4 (0.46) | ALDH1A1FABP4PYCR1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | ALDH1A1 290/4885FABP4 2611/4885PIK3CA 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.