SCHEMBL32688007

SCHEMBL32688007

N#Cc1c(-c2cccc(C(=O)O)c2)cc(=O)[nH]c1SCc1cccc(-c2nnn[nH]2)c1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ACMSD Q8TDX5 13/20 0.49
▸ ADORA1 P30542 3/20 0.43
▸ KMT2A Q03164 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ IKBKB O14920 1/20 0.39
▸ ADORA3 P0DMS8 1/20 0.39
▸ ADORA2A P29274 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20340181 0.90 KMT2A (0.42) ACMSDKMT2AMEN1POLBALDH1A1
SCHEMBL32688124 0.90 ACMSD (0.42) ACMSDADORA1KMT2AMEN1POLB
SCHEMBL20339819 0.87 BRD4 (0.40) ACMSDADORA1KMT2AMEN1POLB
SCHEMBL32688247 0.87 ACMSD (0.44) ACMSDADORA1KMT2AALDH1A1HPGD
SCHEMBL20339912 0.83 ACMSD (0.44) ACMSDKMT2AMEN1POLB
SCHEMBL20340172 0.83 ACMSD (0.61) ACMSDADORA1KMT2AMEN1POLB
SCHEMBL20350857 0.83 ACMSD (0.56) ACMSDADORA1KMT2AMEN1POLB
SCHEMBL26404249 0.83 ALDH1A1 (0.47) ACMSDKMT2AMEN1POLBALDH1A1
SCHEMBL20340099 0.82 KMT2A (0.40) ACMSDKMT2AMEN1POLBALDH1A1
SCHEMBL20340083 0.82 ACMSD (0.49) ACMSDADORA1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK ACMSD 142/4885ADORA1 1595/4885KMT2A 3400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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