Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 9/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688007 | 0.90 | ACMSD (0.49) | ACMSDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL32688271 | 0.88 | ALDH1A1 (0.42) | ACMSDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL20340181 | 0.87 | KMT2A (0.42) | ACMSDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL32688009 | 0.86 | ACMSD (0.54) | ACMSDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL32688394 | 0.85 | NR1H4 (0.48) | ACMSDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL32688164 | 0.83 | KMT2A (0.47) | ACMSDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL20339819 | 0.82 | BRD4 (0.40) | ACMSDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL32688221 | 0.82 | SIRT2 (0.46) | KMT2APOLBMEN1SMN1; SMN2SIRT2 | |
| SCHEMBL32688064 | 0.81 | ACMSD (0.52) | ACMSDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL32688358 | 0.80 | PSMD14 (0.43) | POLBALDH1A1TSHRSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | ACMSD 142/4885KMT2A 3400/4885POLB 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.