SCHEMBL32688056

SCHEMBL32688056

N#Cc1c(-c2ccc(C(=O)Nc3ccccc3)cc2)cc(=O)[nH]c1SCc1nnn[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 10/20 0.41
▸ KDR P35968 10/20 0.41
▸ KMT2A Q03164 4/20 0.41
▸ POLB P06746 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ HDAC6 Q9UBN7 1/20 0.39
▸ LMNA P02545 2/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ MAPT P10636 2/20 0.37
▸ RXFP1 Q9HBX9 1/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ HTT P42858 2/20 0.37
▸ GAA P10253 1/20 0.37
▸ CRHBP P24387 1/20 0.37
▸ CRHR2 Q13324 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688271 0.92 ALDH1A1 (0.42) METKDRKMT2APOLBALDH1A1
SCHEMBL32688138 0.88 KMT2A (0.41) KMT2APOLBALDH1A1HPGDLMNA
SCHEMBL32687977 0.87 KMT2A (0.39) METKDRKMT2APOLBALDH1A1
SCHEMBL32688238 0.85 PTPN1 (0.39) METKDRKMT2AHPGDLMNA
SCHEMBL32688221 0.85 SIRT2 (0.46) METKDRKMT2APOLBMAPT
SCHEMBL32688254 0.84 UGCG (0.40) KMT2APOLBMAPTMEN1HTT
SCHEMBL32688358 0.83 PSMD14 (0.43) METKDRPOLBALDH1A1LMNA
SCHEMBL32688016 0.82 KISS1R (0.42) METKDRKMT2APOLBALDH1A1
SCHEMBL32688247 0.81 ACMSD (0.44) KMT2AALDH1A1HPGD
SCHEMBL32687986 0.81 KMT2A (0.39) KMT2APOLBALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK MET 371/4885KDR 203/4885KMT2A 3400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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