SCHEMBL32688119

SCHEMBL32688119

CCOC(=O)CC(=O)c1ccc(-c2ccccc2)nc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.56
LDHA P00338 2/20 0.55
HPGDS O60760 1/20 0.51
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
HTT P42858 1/20 0.48
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
MAPT P10636 3/20 0.45
ALDH1A1 P00352 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1222552 0.83 NPC1 (0.62) BAZ2BLDHAHPGDSNPC1RAB9A
SCHEMBL4270804 0.81 MAPT (0.61) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL29939457 0.80 HDAC1 (0.51) HDAC1HDAC6MAPTALDH1A1MEN1
SCHEMBL10662120 0.80 HDAC1 (0.51) HDAC1HDAC6MAPTALDH1A1MEN1
SCHEMBL16496366 0.79 HPGDS (0.56) BAZ2BLDHAHPGDSHDAC1SMN1; SMN2
SCHEMBL23149723 0.79 GRN (0.51) HPGDSMAPT
SCHEMBL72371 0.79 WNT3A (0.55) PARP1MAPK1TSHR
SCHEMBL30786512 0.79 KDM4E (0.56) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL23149647 0.79 KDM4E (0.56) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL23149668 0.79 ALDH1A1 (0.47) NPC1RAB9ASMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK BAZ2B 1581/4885LDHA 551/4885HPGDS 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.