Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688394 | 0.92 | NR1H4 (0.48) | KMT2APOLBMEN1ACMSDALDH1A1 | |
| SCHEMBL32688012 | 0.90 | ACMSD (0.49) | KMT2APOLBMEN1ACMSDALDH1A1 | |
| SCHEMBL32688009 | 0.88 | ACMSD (0.54) | KMT2APOLBMEN1ACMSDALDH1A1 | |
| SCHEMBL32688277 | 0.87 | KMT2A (0.52) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL32688064 | 0.86 | ACMSD (0.52) | KMT2APOLBMEN1ACMSDALDH1A1 | |
| SCHEMBL32688124 | 0.83 | ACMSD (0.42) | KMT2APOLBMEN1ACMSDALDH1A1 | |
| SCHEMBL32688364 | 0.82 | KMT2A (0.51) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL20339582 | 0.80 | KMT2A (0.64) | KMT2APOLBMEN1ACMSDALDH1A1 | |
| SCHEMBL32688306 | 0.80 | KMT2A (0.59) | KMT2APOLBMEN1ACMSDALDH1A1 | |
| SCHEMBL32688271 | 0.79 | ALDH1A1 (0.42) | KMT2APOLBMEN1ACMSDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | KMT2A 3400/4885POLB 508/4885MEN1 4353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.