Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32687972 | 0.90 | HSD11B1 (0.38) | HSD11B1CXCR2NOTUMCHRM5CX3CR1 | |
| SCHEMBL32688295 | 0.89 | CXCR2 (0.36) | HSD11B1CXCR2NOTUMCHRM5CX3CR1 | |
| SCHEMBL32688428 | 0.87 | CXCR2 (0.38) | HSD11B1CXCR2NOTUMCHRM5CX3CR1 | |
| SCHEMBL32688106 | 0.84 | ALDH1A1 (0.38) | CXCR2ALDH1A1HPGD | |
| SCHEMBL32688132 | 0.83 | CXCR2 (0.36) | HSD11B1CXCR2NOTUMCHRM5CX3CR1 | |
| SCHEMBL32688235 | 0.81 | HSD11B1 (0.45) | HSD11B1CXCR2ALDH1A1 | |
| SCHEMBL32688370 | 0.77 | POLB (0.41) | HSD11B1CXCR2ALDH1A1HPGDHSD11B2 | |
| SCHEMBL32688070 | 0.76 | ACMSD (0.47) | HSD11B1 | |
| SCHEMBL32688035 | 0.76 | MEN1 (0.41) | HSD11B1CXCR2HSD11B2 | |
| SCHEMBL32688008 | 0.74 | MEN1 (0.42) | HSD11B1CXCR2ALDH1A1HPGDHSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | HSD11B1 61/4885CXCR2 2082/4885NOTUM 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.