Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GRK6 | P43250 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688073 | 0.85 | KDM4E (0.57) | KDM4EKMT2APTGESALDH1A1TDP1 | |
| SCHEMBL7815045 | 0.78 | KDM4E (0.97) | KDM4EKMT2APTGESALDH1A1TDP1 | |
| SCHEMBL32688002 | 0.77 | ACMSD (0.70) | KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11887756 | 0.75 | KDM4E (0.57) | KDM4EKMT2APTGESPRKAG1PRKAA2 | |
| SCHEMBL32688027 | 0.72 | MEN1 (0.66) | KMT2ATDP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL13381566 | 0.72 | HPGD (0.77) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL29770390 | 0.71 | KMT2A (1.00) | KMT2AALDH1A1TDP1HPGDLMNA | |
| SCHEMBL3515244 | 0.71 | KMT2A (1.00) | KMT2AALDH1A1TDP1HPGDLMNA | |
| SCHEMBL5126044 | 0.70 | KMT2A (0.54) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL16772467 | 0.69 | MEN1 (0.72) | KMT2AALDH1A1HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | KDM4E 3207/4885KMT2A 3400/4885PTGES 1546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.