Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | ACMSD | Q8TDX5 | 6/20 | 0.55 |
| ▸ | CTSB | P07858 | 5/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688002 | 0.88 | ACMSD (0.70) | MEN1KMT2APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL32688032 | 0.77 | MEN1 (0.74) | MEN1KMT2APOLBNPC1LMNA | |
| SCHEMBL32688073 | 0.77 | KDM4E (0.57) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL23050907 | 0.76 | LMNA (0.61) | MEN1KMT2APOLBNPC1LMNA | |
| SCHEMBL32688156 | 0.74 | CTSB (0.47) | NPC1RAB9ASMN1; SMN2ACMSDCTSB | |
| SCHEMBL32688395 | 0.72 | KDM4E (0.62) | KMT2ALMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL5106058 | 0.72 | NPC1 (0.74) | MEN1KMT2APOLBNPC1LMNA | |
| SCHEMBL5106063 | 0.72 | RAB9A (0.74) | MEN1KMT2APOLBNPC1LMNA | |
| SCHEMBL5507309 | 0.71 | RAB9A (0.73) | MEN1KMT2APOLBNPC1LMNA | |
| SCHEMBL20339582 | 0.71 | KMT2A (0.64) | MEN1KMT2APOLBNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | MEN1 4353/4885KMT2A 3400/4885POLB 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.