SCHEMBL3269045

SCHEMBL3269045

C1CCC(N(C2CCCCC2)[SiH](N(C2CCCCC2)C2CCCCC2)N(C2CCCCC2)C2CCCCC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 9/20 0.38
ADH1C P00326 6/20 0.36
PHGDH O43175 2/20 0.35
ADH4 P08319 1/20 0.33
ADH1B P00325 1/20 0.32
FDPS P14324 1/20 0.32
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10653280 0.97 ADH1A (0.36) ADH1AADH1CPHGDHADH4
SCHEMBL10652656 0.75 ADH1A (0.39) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL10652524 0.71 ADH1A (0.35) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL10712261 0.71 ADH1A (0.35) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL888444 0.69 ADH1A (0.34) ADH1AADH1CPHGDHADH1BFAAH
SCHEMBL1042621 0.69
SCHEMBL14236885 0.69 ADH1A (0.39) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL4210987 0.69 ADH1A (0.44) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL19591972 0.67 ADH1A (0.43) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL97243 0.67 ADH1A (0.43) ADH1AADH1CPHGDHADH4ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120277457-A1 AMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-11-01 US disclosed
EP-1894934-B1 Stabilization of Nitrogen-Containing and Oxygen-Containing Organosilanes Using Weakly Basic Ion-Exchange Resins AIR PROD & CHEM (US) 2010-06-16 EP disclosed
CN-100384858-C Producing and purifying method of bi (Tert-butyl amino) silane AIR PROD & CHEM (US) 2008-04-30 CN disclosed
EP-1439180-B1 Process for the production and purification of bis(tertiary-butylamino)silane AIR PROD & CHEM (US) 2007-03-28 EP disclosed
US-6963006-B2 Process for the production and purification of bis(tertiary-butylamino)silane AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-11-08 US disclosed
CN-1517352-A Producing and purifying method of bi (Tert-butyl amino) silane �����Ʒ�뻯ѧ��˾ 2004-08-04 CN disclosed
EP-1439180-A1 Process for the production and purification of bis(tertiary-butylamino)silane AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-07-21 EP disclosed
US-20040138491-A1 Process for the production and purification of bis(tertiary-butylamino)silane VERSUM MATERIALS US, LLC 2004-07-15 US disclosed
EP-0228095-B1 PROCESS FOR THE PREPARATION OF OLEFINIC SILANES AND SILOXANES UNION CARBIDE CORPORATION (US) 1992-01-22 EP disclosed
EP-0228095-A2 Process for the preparation of olefinic silanes and siloxanes UNION CARBIDE CORPORATION (US) 1987-07-08 EP disclosed
US-4668812-A Process for the preparation of olefinic silanes and siloxanes UNION CARBIDE CORPORATION (US) 1987-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120277457-A1 AMINOSILANES AND METHODS FOR MAKING SAME NBAS, SFN, SPNS2 ADH1A 2326/4885ADH1C 3364/4885PHGDH 4290/4885
US-20040138491-A1 Process for the production and purification of bis(tertiary-butylamino)silane TERT, BCAT2, TBCA ADH1A 598/4885ADH1C 1024/4885PHGDH 2051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.