Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3270007 | 0.88 | EDNRA (0.44) | PIK3CATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3269782 | 0.88 | TYMS (0.41) | TYMSMAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL3269846 | 0.87 | TYMS (0.39) | TYMSMAPTTP53TUBB4ATUBB | |
| SCHEMBL3268800 | 0.86 | RHEB (0.39) | TYMSTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3183862 | 0.84 | TYMS (0.43) | TYMSPIK3CAMAPTL3MBTL1EPHX1 | |
| SCHEMBL27694239 | 0.79 | TYMS (0.39) | TYMSPIK3CAEPHX1CDC7 | |
| SCHEMBL3272659 | 0.78 | EDNRA (0.44) | PIK3CATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4036741 | 0.77 | RAF1 (0.45) | TYMSTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4035517 | 0.76 | TYMS (0.37) | TYMSPIK3CAEPHX1SLC6A9HAO1 | |
| SCHEMBL3269356 | 0.75 | TYMS (0.35) | TYMSTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784409-B1 | SUBSTITUTED THIENOPYRROLE CARBOXYLIC ACID AMIDES, PYRROLOTHIAZOLE CARBOXYLIC ACID AMIDES, AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMA INC (US) | 2010-06-16 | — | — | EP | claimed |