SCHEMBL3269978

SCHEMBL3269978

C=C(C)C(=O)Oc1ccc(S(=O)(=O)N(CC)CC)cc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.59
HTT P42858 4/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
ALDH1A1 P00352 4/20 0.47
HPGD P15428 2/20 0.47
TSHR P16473 2/20 0.47
ELANE P08246 1/20 0.47
TAS2R14 Q9NYV8 1/20 0.46
NPY2R P49146 1/20 0.45
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3269510 0.83 ALDH1A1 (0.52) LMNAHTTSMN1; SMN2NPC1RAB9A
SCHEMBL3275099 0.83 ALDH1A1 (0.56) LMNAHTTSMN1; SMN2NPC1RAB9A
SCHEMBL29323749 0.81 ELANE (0.51) LMNAHTTSMN1; SMN2ALDH1A1ELANE
SCHEMBL21472366 0.80 SMN1; SMN2 (0.43) LMNAHTTSMN1; SMN2NPC1RAB9A
SCHEMBL1232411 0.79 PKM (0.67) LMNAHTTSMN1; SMN2ALDH1A1ELANE
SCHEMBL1436154 0.78 ELANE (0.54) LMNAHTTSMN1; SMN2ALDH1A1TSHR
Butane SCHEMBL15309676 0.77 ELANE (0.61) LMNAHTTSMN1; SMN2RAB9AALDH1A1
SCHEMBL56436 0.77 ELANE (0.69) LMNAHTTSMN1; SMN2RAB9AALDH1A1
SCHEMBL3248031 0.77 ALDH1A1 (0.50) LMNASMN1; SMN2ALDH1A1TSHRELANE
SCHEMBL7184942 0.76 ELANE (0.53) LMNAHTTSMN1; SMN2ALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-06-14 US disclosed
EP-1972440-B1 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM CORP (JP) 2010-06-23 EP disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE EIF3L, EIF2B1, EIF2B5 LMNA 780/4885HTT 4556/4885SMN1; SMN2 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.