Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567133 | 0.87 | LMNA (0.46) | KDM4EALDH1A1MAPTKMT2AGSR | |
| Bicarbonate SCHEMBL27706335 | 0.81 | CES2 (0.46) | ALDH1A1GSRLMNA | |
| SCHEMBL10653829 | 0.76 | ACHE (0.43) | KDM4EHSD17B10CNR1ALDH1A1MAPT | |
| SCHEMBL11440190 | 0.76 | GSR (0.37) | KDM4EALDH1A1MAPTKMT2AGSR | |
| SCHEMBL5053923 | 0.76 | IDO1 (0.44) | HSD17B10CNR1ALDH1A1MAPTGAA | |
| SCHEMBL460268 | 0.76 | SLC6A2 (0.53) | SLC6A3SLC6A2SLC6A4KDM4ECNR1 | |
| SCHEMBL15216574 | 0.74 | SLC6A2 (0.62) | SLC6A3SLC6A2SLC6A4CNR1ALDH1A1 | |
| SCHEMBL17911851 | 0.72 | ADRA2A (0.41) | SLC6A3SLC6A2SLC6A4CNR1KMT2A | |
| SCHEMBL7944964 | 0.72 | CNR1 (0.37) | SLC6A3KDM4ECNR1ALDH1A1MAPT | |
| SCHEMBL15055313 | 0.72 | CNR1 (0.40) | SLC6A3KDM4ECNR1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9322001-B2 | Cytochrome P450 oxygenases | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-04-26 | — | — | US | disclosed |
| US-20140322792-A1 | CYTOCHROME P450 OXYGENASES | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-30 | — | — | US | disclosed |
| US-8722371-B2 | Cytochrome P450 oxygenases | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130288324-A1 | CYTOCHROME P450 OXYGENASES | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-10-31 | — | — | US | disclosed |
| US-8367386-B2 | Cytochrome P450 oxygenases | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120184015-A1 | CYTOCHROME P450 OXYGENASES | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-07-19 | — | — | US | disclosed |
| US-8076114-B2 | Cytochrome P450 oxygenases | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-12-13 | — | — | US | disclosed |
| US-20100248327-A1 | CYTOCHROME P450 OXYGENASES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-09-30 | — | — | US | disclosed |
| US-7691616-B2 | Enzymatic polypeptide for use in the oxidation of alkanes and alkenes of eight or less carbons and are resistant to organic solvents | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080293928-A1 | Cytochrom P450 oxygenases | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2008-11-27 | — | — | US | disclosed |
| US-7226768-B2 | Enzymetic polypeptide for use in the oxidation of alkanes and alkenes of eight or less carbons | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-05 | — | — | US | disclosed |
| WO-2003008563-A9 | IMPROVED CYTOCHROME P450 OXYGENASES | CALIFORNIA INST OF TECHN (US) | 2003-08-14 | — | — | WO | disclosed |
| US-20030100744-A1 | Enzymetic polypeptide for use in the oxidation of alkanes and alkenes of eight or less carbons | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-05-29 | — | — | US | disclosed |
| WO-2003008563-A2 | IMPROVED CYTOCHROME P450 OXYGENASES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-01-30 | — | — | WO | disclosed |
| EP-1279956-A2 | Determination of Epoxides and Aldehydes in gases | BAYER AG (DE) | 2003-01-29 | — | — | EP | disclosed |