Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15055313 | 0.96 | CNR1 (0.40) | CNR1MAPTKMT2ANPSR1LMNA | |
| SCHEMBL10567133 | 0.78 | LMNA (0.46) | MAPTKMT2ANPSR1LMNAMEN1 | |
| Bicarbonate SCHEMBL27706335 | 0.72 | CES2 (0.46) | LMNATDP1GSRALDH1A1CES2 | |
| SCHEMBL3271045 | 0.72 | SLC6A3 (0.54) | CNR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL28734597 | 0.70 | MAPT (0.53) | CNR1MAPTALDH1A1OPRM1OPRD1 | |
| SCHEMBL10653829 | 0.68 | ACHE (0.43) | CNR1MAPTKMT2ANPSR1LMNA | |
| SCHEMBL11655685 | 0.68 | ALOX5 (0.42) | CNR1MAPTKMT2ANPSR1LMNA | |
| SCHEMBL11440190 | 0.68 | GSR (0.37) | MAPTKMT2ANPSR1LMNAMEN1 | |
| SCHEMBL5053923 | 0.68 | IDO1 (0.44) | CNR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL31065464 | 0.66 | MAPT (0.57) | CNR1MAPTLMNAOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242428-B1 | NUCLEOSIDES AND NUCLEOSIDE DIMERS CONTAINING AN L-SUGAR IN AT LEAST ONE OF THE NUCLEOSIDES | UNISEARCH LIMITED (AU) | 2001-06-05 | — | — | US | claimed |