Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3270267 | 0.90 | S1PR1 (0.56) | S1PR1ALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL2816974 | 0.88 | CRHBP (0.61) | ALDH1A1TDP1CRHBPCRHR2HPRT1 | |
| SCHEMBL13309518 | 0.88 | ALDH1A1 (0.59) | S1PR1ALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL3276362 | 0.83 | TDP1 (0.66) | ALDH1A1TDP1CRHBPCRHR2HPRT1 | |
| SCHEMBL30352851 | 0.83 | TDP1 (0.66) | ALDH1A1TDP1CRHBPCRHR2HPRT1 | |
| SCHEMBL15203036 | 0.82 | CRHBP (0.58) | ALDH1A1TDP1CRHBPCRHR2HSD17B10 | |
| SCHEMBL1514401 | 0.82 | CRHBP (0.58) | ALDH1A1TDP1CRHBPCRHR2HSD17B10 | |
| SCHEMBL15791110 | 0.81 | TDP1 (0.53) | ALDH1A1TDP1CRHBPCRHR2HPRT1 | |
| SCHEMBL2360248 | 0.79 | HSD17B10 (0.69) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL30564320 | 0.79 | HSD17B10 (0.69) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343637-B2 | Carbazole derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| EP-2102309-B1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-06-30 | — | — | EP | disclosed |
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-2102309-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008086851-A1 | CARBAZOLE DERIVATIVES FOR ORGANC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, CACNA2D1, CYCS | S1PR1 3546/4885ALDH1A1 208/4885TDP1 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.