Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3273771 | 1.00 | KCNMA1 (0.46) | KCNMA1LTB4RPYGLKDM1AGPR35 | |
| SCHEMBL3277357 | 0.84 | TRPM2 (0.40) | TRPM2KDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL3277364 | 0.84 | TRPM2 (0.40) | TRPM2KDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL4557459 | 0.79 | KDM1A (0.50) | PYGLKDM1AGPR35XDHALDH1A1 | |
| SCHEMBL3273276 | 0.77 | GPR35 (0.59) | KCNMA1GPR35KDM4EMEN1KMT2A | |
| SCHEMBL3273270 | 0.77 | GPR35 (0.59) | KCNMA1GPR35KDM4EMEN1KMT2A | |
| SCHEMBL3274593 | 0.70 | CHRNA7 (0.54) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3274588 | 0.70 | CHRNA7 (0.54) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2892700 | 0.68 | GPR35 (0.71) | KCNMA1GPR35 | |
| SCHEMBL3274304 | 0.68 | KDM4E (0.40) | TRPM2KDM4EMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-08 | — | — | US | claimed |
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | TRPV1, TRPA1, TRPM8 | KCNMA1 103/4885LTB4R 2132/4885PYGL 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.