Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | QDPR | P09417 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | YWHAG | P61981 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138483 | 0.79 | TSHR (0.70) | TSHRMEN1KMT2AMAPK1CYP3A4 | |
| SCHEMBL30669503 | 0.79 | TSHR (0.70) | TSHRMEN1KMT2AMAPK1CYP3A4 | |
| SCHEMBL13414991 | 0.79 | TSHR (0.91) | TSHRQDPRPTPN1ALOX5GAA | |
| SCHEMBL7632848 | 0.78 | TSHR (0.44) | TSHRGAAPOLBKMT2AMAPK1 | |
| SCHEMBL327401 | 0.77 | ALDH1A1 (0.52) | TSHRGAAPOLBMEN1KMT2A | |
| SCHEMBL21280037 | 0.74 | TSHR (0.45) | TSHRMEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL9270618 | 0.72 | TSHR (0.46) | TSHRGAAPOLBMEN1KMT2A | |
| SCHEMBL9270773 | 0.71 | KDM4E (0.49) | TSHRCYP3A4KDM4E | |
| SCHEMBL16597325 | 0.71 | TSHR (0.85) | TSHRQDPRPTPN1ALOX5GAA | |
| SCHEMBL9266484 | 0.69 | MAPT (0.50) | TSHRALOX5POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11117987-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2021-09-14 | — | — | US | disclosed |
| US-11028195-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2021-06-08 | — | — | US | disclosed |
| US-20190322777-A1 | Hydroxyaryl Functionalized Polymers | BRIDGESTONE CORPORATION (JP) | 2019-10-24 | — | — | US | disclosed |
| US-20190233557-A1 | Hydroxyaryl Functionalized Polymers | BRIDGESTONE CORPORATION (JP) | 2019-08-01 | — | — | US | disclosed |
| US-10227425-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2019-03-12 | — | — | US | disclosed |
| US-20150141582-A1 | Hydroxyaryl Functionalized Polymers | BRIDGESTONE CORPORATION (JP) | 2015-05-21 | — | — | US | disclosed |
| US-20150141582-A1 | Hydroxyaryl Functionalized Polymers | BRIDGESTONE CORPORATION (JP) | 2015-05-21 | — | — | US | disclosed |
| US-8871871-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2014-10-28 | — | — | US | disclosed |
| US-8871871-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2014-10-28 | — | — | US | disclosed |
| US-7842830-B2 | Transition-metal charge-transport materials, methods of fabrication thereof, and methods of use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-11-30 | — | — | US | disclosed |
| US-20100286348-A1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286348-A1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20080121870-A1 | Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof | GEORGIA TECH RESEACH CORPORATION | 2008-05-29 | — | — | US | disclosed |
| EP-1004623-A1 | Aryl thioacetals useful as stabilizers in polymeric materials | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322777-A1 | Hydroxyaryl Functionalized Polymers | HAAO, HCAR3, VCL | TSHR 3633/4885QDPR 2692/4885PTPN1 1077/4885 |
| US-11028195-B2 | Hydroxyaryl functionalized polymers | HAAO, HCAR3, VCL | TSHR 3597/4885QDPR 2846/4885PTPN1 1207/4885 |
| US-10227425-B2 | Hydroxyaryl functionalized polymers | HAAO, HCAR3, VCL | TSHR 3633/4885QDPR 2692/4885PTPN1 1077/4885 |
| US-20150141582-A1 | Hydroxyaryl Functionalized Polymers | HAAO, HCAR3, VCL | TSHR 3633/4885QDPR 2692/4885PTPN1 1077/4885 |
| US-20080121870-A1 | Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof | SLC39A3, SLC6A6, SLC6A9 | TSHR 4527/4885QDPR 4284/4885PTPN1 4475/4885 |
| US-20100286348-A1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | HAAO, HCAR3, VCL | TSHR 3633/4885QDPR 2692/4885PTPN1 1077/4885 |
| US-11117987-B2 | Hydroxyaryl functionalized polymers | HAAO, HCAR3, VCL | TSHR 3633/4885QDPR 2692/4885PTPN1 1077/4885 |
| US-20190233557-A1 | Hydroxyaryl Functionalized Polymers | HAAO, HCAR3, VCL | TSHR 3597/4885QDPR 2846/4885PTPN1 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.