SCHEMBL9065300

SCHEMBL9065300

CC(Cl)OC(=O)CC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.36
SRR Q9GZT4 1/20 0.36
FAAH O00519 4/20 0.33
TSHR P16473 3/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33
MMP13 P45452 1/20 0.33
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
PTGS2 P35354 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065292 0.87 MGAM (0.38) FAAHTSHRMMP1MMP2MMP3
SCHEMBL11278832 0.81 MGAM (0.50) FAAHTSHRALDH1A1MAPTTDP1
SCHEMBL3279260 0.81 MGAM (0.50) FAAHTSHRALDH1A1MAPTTDP1
SCHEMBL7463374 0.80 LDHA (0.40) LDHASRRTSHRMMP1MMP2
SCHEMBL242500 0.80 TSHR (0.47) LDHASRRTSHRMMP1MMP2
SCHEMBL14661595 0.79 EGLN1 (0.45) TSHRMMP1MMP2MMP3MMP9
SCHEMBL5349565 0.78 LDHA (0.38) LDHASRRFAAHTSHRMMP1
SCHEMBL7264660 0.77 FAAH (0.54) FAAHTSHRALDH1A1CNR1CNR2
SCHEMBL11601735 0.77 LMNA (0.41) TSHRMMP1MMP2MMP3MMP9
SCHEMBL5859547 0.76 MMP1 (0.38) LDHASRRFAAHTSHRMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107118183-B Synthesis method of tetrahydro-3-furanmethanol 成都化润药业有限公司 2021-02-02 CN claimed
CN-107793383-A A kind of preparation method of 3 hydroxymethyl tetrahydrofuran 成都化润药业有限公司 2018-03-13 CN claimed
CN-107118183-A A kind of synthetic method of the furancarbinol of tetrahydrochysene 3 成都化润药业有限公司 2017-09-01 CN claimed
EP-4554931-A1 PROCESS FOR PREPARING SUBSTITUTED BENZAMIDES ADAMA MAKHTESHIM LTD. (IL) 2025-05-21 EP disclosed
CN-119698408-A Process for preparing substituted benzamides 安道麦马克西姆有限公司 2025-03-25 CN disclosed
WO-2024013736-A1 PROCESS FOR PREPARING SUBSTITUTED BENZAMIDES ADAMA MAKHTESHIM LTD. (IL) 2024-01-18 WO disclosed
CN-107118183-B Synthesis method of tetrahydro-3-furanmethanol 成都化润药业有限公司 2021-02-02 CN disclosed
CN-107118183-B Synthesis method of tetrahydro-3-furanmethanol 成都化润药业有限公司 2021-02-02 CN disclosed
CN-109225191-A A kind of method and its catalyst preparing dinotefuran intermediate 3- hydroxymethyl tetrahydrofuran 河南省农村科学技术开发中心有限责任公司 2019-01-18 CN disclosed
CN-107793383-A A kind of preparation method of 3 hydroxymethyl tetrahydrofuran 成都化润药业有限公司 2018-03-13 CN disclosed
CN-107793383-A A kind of preparation method of 3 hydroxymethyl tetrahydrofuran 成都化润药业有限公司 2018-03-13 CN disclosed
CN-107118183-A A kind of synthetic method of the furancarbinol of tetrahydrochysene 3 成都化润药业有限公司 2017-09-01 CN disclosed
CN-107118183-A A kind of synthetic method of the furancarbinol of tetrahydrochysene 3 成都化润药业有限公司 2017-09-01 CN disclosed
CN-1247594-C Bicyclic heteroaromatic compounds OKZO NOBEL N V (NL) 2006-03-29 CN disclosed
CN-1462273-A Bicyclic heteroaromatic compounds OKZO NOBEL N V (NL) 2003-12-17 CN disclosed
US-5569780-A Dialkyl 2-haloethyl malonates HULS AKTIENGESELLSCHAFT (DE) 1996-10-29 US disclosed
US-5463111-A Process for preparing dialkyl 2-haloethyl malonates HULS AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed