SCHEMBL3279758

SCHEMBL3279758

O=P(O)(OCl)Oc1cc2ccccc2[nH]1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.42
KDM4E B2RXH2 4/20 0.41
DAO P14920 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
SRD5A2 P31213 1/20 0.41
HSD17B10 Q99714 1/20 0.41
DDO Q99489 1/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 1/20 0.41
MAPK1 P28482 1/20 0.41
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP2A6 P11509 1/20 0.39
AOC3 Q16853 2/20 0.38
TP53 P04637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrazole SCHEMBL9442035 0.87 FLT3 (0.33) FLT3KDM4EDAOMAPTHPGD
SCHEMBL367083 0.85 FLT3 (0.46) FLT3KDM4EDAOMAPTHPGD
SCHEMBL18486436 0.82 FLT3 (0.34) FLT3KDM4EDAOMAPTHPGD
SCHEMBL18486604 0.81 KDM4E (0.33) FLT3KDM4EDAOMAPTHPGD
SCHEMBL1470509 0.81 FLT3 (0.44) FLT3KDM4EDAOMAPTHPGD
SCHEMBL7848676 0.80 FLT3 (0.39) FLT3KDM4EDAOMAPTHPGD
SCHEMBL5185736 0.80 FLT3 (0.41) FLT3NPC1CYP2A6KDRMEN1
SCHEMBL434362 0.80 RAB9A (0.37) FLT3KDM4EDAOMAPTHPGD
SCHEMBL28281829 0.78 GPR84 (0.43) FLT3KDM4EDAOMAPTHPGD
SCHEMBL29246527 0.76 SLC22A6 (0.43) FLT3GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3080272-A1 APTAMER-GATED NANOPARTICLES FOR LATERAL FLOW ASSAYS Nanobiz Nanobiyoteknolojik Sistemler Egitim Bilisim Danismanlik Arge San.Tic. Ltd. Sti. (TR) 2016-10-19 EP claimed
WO-2015088455-A1 APTAMER-GATED NANOPARTICLES FOR LATERAL FLOW ASSAYS NANOBIZ NANOBIYOTEKNOLOJIK SISTEMLER EGITIM BILISIM DANISMANLIK AR-GE SAN.TIC. LTD. STI. (TR) 2015-06-18 WO claimed
EP-1724281-B1 PATHOGENIC INFECTION DETECTION COMPOSITIONS AND METHODS BIOKIT SA (ES) 2013-02-13 EP disclosed
US-7700727-B2 Compositions and kits for detecting pathogen infection BIOKIT, S.A. (ES) 2010-04-20 US disclosed
US-20060286119-A1 Compositions and methods for treatment of chronic and infectious diseases BIOKIT S.A. (ES) 2006-12-21 US disclosed
US-20060275317-A1 Vaccine compositions for prevention of chronic and infectious diseases BIOKIT S.A. (ES) 2006-12-07 US disclosed
US-20060269976-A1 METHOD FOR REDUCING LYSOZYME ENZYMATIC ACTIVITY BIOKIT S.A. (ES) 2006-11-30 US disclosed
US-20060270835-A1 Diagnosis and treatment of Alzheimer disease BIOKIT S.A. (ES) 2006-11-30 US disclosed
EP-1724281-A1 PATHOGENIC INFECTION DETECTION COMPOSITIONS AND METHODS Biokit S.A. (ES) 2006-11-22 EP disclosed
US-20060063149-A1 Compositions and methods for detecting pathogen infection Patent Administrator 2006-03-23 US disclosed
US-20050277181-A1 Compositions and methods for detecting pathogen infection BIOKIT S.A. (ES) 2005-12-15 US disclosed
US-20030153019-A1 Method and device for identifying a mycobacterium species responsible for a mycobacterial infection RAPID MEDICAL DIAGNOSTICS, INC. 2003-08-14 US disclosed
US-6416962-B1 PROVIDING PREPARATION OF MYCOBACTERIUM SPECIES COMPRISING IMMUNO-CROSS-REACTIVE ANTIGEN COMPONENTS BOUND TO SOLID CARRIER, CONTACTING WITH TEST SAMPLE CONTAINING ANTIBODIES, DETECTING ANTIBODY-ANTIGEN BINDING TO IDENTIFY SPECIES KREATECH BIOTECHNOLOGY B.V. (NL) 2002-07-09 US disclosed
EP-0674766-B1 METHOD AND DEVICE FOR IDENTIFYING A MYCOBACTERIUM SPECIES RESPONSIBLE FOR A MYCOBACTERIAL INFECTION KREATECH BIOTECH BV (NL) 2000-04-26 EP disclosed
US-5817473-A FORMING ANTIGEN-ANTIBODY COMPLEX KREATECH BIOTECHNOLOGY B.V. (NL) 1998-10-06 US disclosed
EP-0674766-A1 METHOD AND DEVICE FOR IDENTIFYING A MYCOBACTERIUM SPECIES RESPONSIBLE FOR A MYCOBACTERIAL INFECTION KREATECH BIOTECHNOLOGY B.V. (NL) 1995-10-04 EP disclosed
WO-1994014069-A1 METHOD AND DEVICE FOR IDENTIFYING A MYCOBACTERIUM SPECIES RESPONSIBLE FOR A MYCOBACTERIAL INFECTION KREATECH BIOTECHNOLOGY B.V. (NL) 1994-06-23 WO disclosed
US-5242820-A Pathogenic mycoplasma AMERICAN REGISTRY OF PATHOLOGY (US) 1993-09-07 US disclosed
EP-0242264-A1 Non-radioactive, single-stranded labelled probe, method for its production and method of detecting a target nucleotide sequence using this probe INSTITUT PASTEUR (FR) 1987-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063149-A1 Compositions and methods for detecting pathogen infection TREH, IL17A, TLL1 FLT3 2157/4885KDM4E 4716/4885DAO 1645/4885
US-20060275317-A1 Vaccine compositions for prevention of chronic and infectious diseases IL17A, TREH, MMP17 FLT3 2540/4885KDM4E 4722/4885DAO 2735/4885
US-20060269976-A1 METHOD FOR REDUCING LYSOZYME ENZYMATIC ACTIVITY TREH, PEPD, MMP17 FLT3 3022/4885KDM4E 4359/4885DAO 733/4885
US-20060286119-A1 Compositions and methods for treatment of chronic and infectious diseases IL17A, TREH, TLL1 FLT3 2382/4885KDM4E 4813/4885DAO 1546/4885
US-20050277181-A1 Compositions and methods for detecting pathogen infection TREH, IL17A, TLL1 FLT3 2157/4885KDM4E 4716/4885DAO 1645/4885
US-20060270835-A1 Diagnosis and treatment of Alzheimer disease PSEN1, APP, MMP17 FLT3 3325/4885KDM4E 4652/4885DAO 1450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.