Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11912053 | 0.83 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1PAOXCHRM1 | |
| SCHEMBL13588704 | 0.83 | KMT2A (0.39) | KMT2AMEN1 | |
| SCHEMBL12602742 | 0.81 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1PAOXCHRM1 | |
| SCHEMBL25129630 | 0.79 | KMT2A (0.36) | KMT2AMEN1 | |
| SCHEMBL19699903 | 0.78 | KMT2A (0.39) | KMT2AMEN1ALDH1A1PAOXCHRM1 | |
| SCHEMBL12249905 | 0.78 | KMT2A (0.35) | KMT2AMEN1 | |
| SCHEMBL25129700 | 0.78 | KMT2A (0.35) | KMT2AMEN1 | |
| SCHEMBL668762 | 0.77 | UBE2N (0.41) | PAOXCHRM1 | |
| SCHEMBL888729 | 0.76 | ALDH1A1 (0.59) | ALDH1A1PAOXCHRM1TDP1LMNA | |
| SCHEMBL25663959 | 0.76 | PIK3CD (0.45) | KMT2AMEN1ALDH1A1PAOXCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133472-B2 | Cyclopeptides containing RGD mimetics as imaging markers for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20100074844-A1 | Cyclopeptides Containing RGD Mimetics As Imaging Markers For Integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-7666392-B2 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080170992-A1 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100074844-A1 | Cyclopeptides Containing RGD Mimetics As Imaging Markers For Integrins | ITGB3, ITGAV, ITGB1 | KMT2A 4849/4885MEN1 2076/4885ALDH1A1 4178/4885 |
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | ITGB1, ITGAM, ITGB3 | KMT2A 4133/4885MEN1 787/4885ALDH1A1 2416/4885 |
| US-20080170992-A1 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | ITGB3, VCAM1, ITGB1 | KMT2A 4819/4885MEN1 1187/4885ALDH1A1 3523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.