SCHEMBL888729

SCHEMBL888729

CC(=O)CCC(=O)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
LMNA P02545 1/20 0.48
SLC15A2 Q16348 1/20 0.48
TDP1 Q9NUW8 2/20 0.41
ACHE P22303 1/20 0.35
PAOX Q6QHF9 1/20 0.35
TRPA1 O75762 1/20 0.33
CA1 P00915 1/20 0.31
IAPP P10997 1/20 0.30
CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL620412 0.87 CA1 (0.36) ALDH1A1TDP1CA1
SCHEMBL28831888 0.85 ALDH1A1 (0.37) ALDH1A1LMNASLC15A2TDP1CA1
SCHEMBL29259194 0.84 ALDH1A1 (0.42) ALDH1A1LMNASLC15A2TDP1
SCHEMBL11918238 0.83 ALDH1A1 (0.45) ALDH1A1LMNASLC15A2TDP1ACHE
SCHEMBL8817365 0.83 PAOX (0.48) ALDH1A1LMNASLC15A2TDP1ACHE
SCHEMBL9975047 0.81 PAOX (0.52) ALDH1A1ACHEPAOX
SCHEMBL9975042 0.81 PAOX (0.52) ALDH1A1ACHEPAOX
SCHEMBL9975046 0.81 PAOX (0.52) ALDH1A1ACHEPAOX
SCHEMBL24925542 0.78 ALDH1A1 (0.53) ALDH1A1LMNASLC15A2TDP1ACHE
SCHEMBL11918287 0.78 CES1 (0.44) ALDH1A1TDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116219085-B Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2024-03-15 CN claimed
CN-116334320-B Aliphatic synthetic tanning agent containing multifunctional groups and preparation method and application thereof 南京工业大学 2024-02-13 CN claimed
CN-116356085-A Aliphatic synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2023-06-30 CN claimed
CN-116334320-A Aliphatic synthetic tanning agent containing multifunctional groups and preparation method and application thereof 南京工业大学 2023-06-27 CN claimed
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 US claimed
EP-4638148-A1 TIRES FOR VEHICLE WHEELS Pirelli Tyre S.p.A. (IT) 2025-10-29 EP disclosed
US-12030876-B2 Aryl hydrocarbon receptor (AHR) agonists and uses thereof Ikena Oncology, Inc. (US) 2024-07-09 US disclosed
WO-2024134488-A1 TIRES FOR VEHICLE WHEELS PIRELLI TYRE S.P.A. (IT) 2024-06-27 WO disclosed
CN-116334320-B Aliphatic synthetic tanning agent containing multifunctional groups and preparation method and application thereof 南京工业大学 2024-02-13 CN disclosed
CN-117545811-A Non-aqueous crosslinkable compositions 湛新荷兰有限公司 2024-02-09 CN disclosed
US-20230382947-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT UNIVERSITEIT GENT (BE) 2023-11-30 US disclosed
US-20230355775-A1 NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING SAME, PREPARATION METHOD, AND USE THEREOF Suzhou Ribo Life Science Co., Ltd. (CN) 2023-11-09 US disclosed
EP-0654460-A1 Process for the C-alkylation of a ketonic compound RHONE-POULENC CHIMIE (FR) 1995-05-24 EP disclosed
US-5194619-A PROCESS FOR THE PREPARATION OF SUBSTITUTED INDENES HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed
EP-0500005-A1 Process for the preparation of substituted indenes HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-26 EP disclosed
US-4575538-A REACTION PRODUCT OF RARE EARTH HALIDE AND LEWIS BASE AS CATALYST PHILLIPS PETROLEUM COMPANY (US) 1986-03-11 US disclosed
US-4556647-A Olefin polymerization PHILLIPS PETROLEUM COMPANY (US) 1985-12-03 US disclosed
US-4544718-A RARE EARTH HYDROXYHALIDE-CONTAINING CATALYST PHILLIPS PETROLEUM COMPANY (US) 1985-10-01 US disclosed
US-4162258-A INTENSIFIERS FOR FLAVORS AND PERFUMES THE LION DENTIFRICE CO., LTD. (JP) 1979-07-24 US disclosed
US-4035395-A Process for the preparation of ketones BAYER AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030876-B2 Aryl hydrocarbon receptor (AHR) agonists and uses thereof AHR, ARNT, HCAR1 ALDH1A1 289/4885LMNA 3518/4885SLC15A2 2761/4885
US-20230355775-A1 NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING SAME, PREPARATION METHOD, AND USE THEREOF APOB, C1QBP, APOL1 ALDH1A1 3395/4885LMNA 301/4885SLC15A2 3596/4885
US-20230382947-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT DCLRE1A, CNBP, RNGTT ALDH1A1 3895/4885LMNA 2063/4885SLC15A2 3726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.