Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3283097 | 0.85 | KAT8 (0.39) | — | |
| SCHEMBL27539010 | 0.81 | PTGS2 (0.41) | KDM4ETSHRALDH1A1MAPTHPGD | |
| SCHEMBL6888756 | 0.81 | ALDH1A1 (0.35) | KDM4ETSHRALDH1A1GAAMAPT | |
| SCHEMBL6882582 | 0.80 | ALDH1A1 (0.34) | KDM4ETSHRALDH1A1GAAMAPT | |
| SCHEMBL6478273 | 0.79 | VDR (0.38) | — | |
| SCHEMBL27513285 | 0.75 | CALM1 (0.39) | ALOX5LMNA | |
| SCHEMBL3280780 | 0.75 | VDR (0.39) | — | |
| SCHEMBL10735013 | 0.73 | ESRRA (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6888828 | 0.73 | FFAR1 (0.43) | ALOX5 | |
| SCHEMBL26270868 | 0.71 | MAPT (0.51) | CYP4F2CYP4A11KDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| CN-1267394-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2006-08-02 | — | — | CN | disclosed |
| CN-1549803-A | Vitamin D analogues | �������о�����չ˽������˾ | 2004-11-24 | — | — | CN | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |