SCHEMBL3280822

SCHEMBL3280822

CC(=COC1C2CC3CC(C2)CC1C3)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.35
EPHX1 P07099 1/20 0.33
MAPT P10636 1/20 0.33
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16781302 0.78 CYP2C9 (0.40) HSD11B1EPHX1
SCHEMBL2967397 0.74 FDFT1 (0.38) HSD11B1EPHX1MAPT
SCHEMBL2967393 0.74 FDFT1 (0.38) HSD11B1EPHX1MAPT
SCHEMBL9649905 0.71 HSD11B1 (0.38) HSD11B1MAPTEPHX2
SCHEMBL244479 0.71 HSD11B1 (0.38) HSD11B1MAPTEPHX2
SCHEMBL3961156 0.69 HSD11B1 (0.44) HSD11B1EPHX1MAPTEPHX2
SCHEMBL20768339 0.69 HSD11B1 (0.44) HSD11B1EPHX1EPHX2
SCHEMBL2300010 0.68 HSD11B1 (0.43) HSD11B1EPHX1EPHX2
SCHEMBL3753073 0.67 HSD11B1 (0.50) HSD11B1EPHX1EPHX2
SCHEMBL6329865 0.67 HSD11B1 (0.39) HSD11B1EPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741538-B2 Polymer compound, photoresist composition containing such polymer compound, and method for forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2014-06-03 US disclosed
EP-1736485-B1 POLYMER COMPOUND, PHOTORESIST COMPOSITION CONTAINING SUCH POLYMER COMPOUND, AND METHOD FOR FORMING RESIST PATTERN TOKYO OHKA KOGYO CO LTD (JP) 2013-07-31 EP disclosed
US-20100151383-A1 POLYMER COMPOUND, PHOTORESIST COMPOSITION CONTAINING SUCH POLYMER COMPOUND, AND METHOD FOR FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2010-06-17 US disclosed
US-7700259-B2 Polymer compound, photoresist composition containing such polymer compound, and method for forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2010-04-20 US disclosed
US-20070224520-A1 Polymer Compound, Photoresist Composition Containing Such Polymer Compound, and Method for Forming Resist Pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2007-09-27 US disclosed
EP-1736485-A1 POLYMER COMPOUND, PHOTORESIST COMPOSITION CONTAINING SUCH POLYMER COMPOUND, AND METHOD FOR FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2006-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070224520-A1 Polymer Compound, Photoresist Composition Containing Such Polymer Compound, and Method for Forming Resist Pattern ADH1A, ADH1C, POLR1A HSD11B1 354/4885EPHX1 1507/4885MAPT 716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.