Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644250 | 0.90 | ESR1 (0.53) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL2584694 | 0.84 | THRB (0.54) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL202339 | 0.84 | THRB (0.54) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL5899549 | 0.81 | THRB (0.49) | HSD17B10THRBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15803539 | 0.79 | THRB (0.50) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL15803521 | 0.79 | THRB (0.50) | ESR1ESR2CYP3A4ARHPGD | |
| Bisphenol A SCHEMBL28112230 | 0.79 | ESR1 (0.55) | ESR1ESR2CYP3A4ARHPGD | |
| Methoxymethane SCHEMBL9576531 | 0.79 | THRB (0.56) | ESR1ESR2THRBELANEALDH1A1 | |
| SCHEMBL13419121 | 0.79 | RXRA (0.47) | HSD17B10THRBELANEALDH1A1KDM4E | |
| SCHEMBL5899677 | 0.78 | THRB (0.49) | CYP3A4HSD17B10THRBELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709221-B2 | Biosensor with inorganic-organic hybrid polymer coating | FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2010-05-04 | — | — | US | claimed |