Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | MMP7 | P09237 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MMP16 | P51512 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852329 | 0.90 | ALDH1A1 (0.41) | ALDH1A1RAB9AMMP9MMP2ADRB2 | |
| SCHEMBL6865083 | 0.87 | MMP1 (0.48) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL328390 | 0.86 | MMP1 (0.43) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL328407 | 0.86 | MMP1 (0.43) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL10067177 | 0.86 | MMP3 (0.44) | MMP3ALDH1A1RAB9AMMP1MMP13 | |
| SCHEMBL328552 | 0.84 | MMP1 (0.45) | MMP3ALDH1A1MMP1MMP13MMP8 | |
| SCHEMBL6863112 | 0.83 | MMP1 (0.42) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL328649 | 0.83 | MMP1 (0.44) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL6863812 | 0.83 | MMP3 (0.52) | MMP3MMP1MMP13MMP8MMP7 | |
| SCHEMBL10067178 | 0.83 | MMP3 (0.50) | MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |