Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | AHCY | P23526 | 16/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852594 | 0.92 | AHCY (0.44) | MMP3AHCYKDM4ECA12CA9 | |
| SCHEMBL10067173 | 0.89 | MMP3 (0.49) | MMP3AHCY | |
| SCHEMBL328413 | 0.88 | MMP3 (0.51) | MMP3AHCY | |
| SCHEMBL6863812 | 0.86 | MMP3 (0.52) | MMP3AHCYKDM4E | |
| SCHEMBL328492 | 0.84 | MMP1 (0.42) | MMP3CA9 | |
| SCHEMBL328388 | 0.84 | MMP3 (0.43) | MMP3 | |
| SCHEMBL328554 | 0.83 | MMP3 (0.48) | MMP3 | |
| SCHEMBL328398 | 0.83 | MMP3 (0.45) | MMP3 | |
| SCHEMBL6864692 | 0.82 | MMP3 (0.50) | MMP3KDM4E | |
| SCHEMBL328400 | 0.81 | MMP3 (0.51) | MMP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |