Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618804 | 0.77 | ADRB2 (0.50) | ESR2ADRB2ALDH1A1HTTESR1 | |
| SCHEMBL12980868 | 0.71 | TSHR (0.52) | NR3C1ESR2OPRL1 | |
| SCHEMBL22500202 | 0.69 | ESR2 (0.44) | NR3C1ARESR2GRIN2BGRIN2D | |
| SCHEMBL7906825 | 0.69 | ESR1 (0.53) | ESR2ADRB2ALDH1A1HTTESR1 | |
| SCHEMBL12982717 | 0.69 | KDM1A (0.45) | NR3C1ALDH1A1OPRL1 | |
| SCHEMBL5267941 | 0.66 | DPP4 (0.61) | OPRL1 | |
| SCHEMBL10606332 | 0.66 | DPP4 (0.55) | OPRL1 | |
| SCHEMBL12982312 | 0.65 | MAOA (0.44) | NR3C1HTTOPRL1 | |
| SCHEMBL12981322 | 0.65 | MAOA (0.44) | NR3C1ESR2ALDH1A1HTTOPRL1 | |
| SCHEMBL49169 | 0.65 | DPP4 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713989-B2 | Glucocorticoid receptor modulators | DOW ROBERT L | 2010-05-11 | — | — | US | disclosed |
| US-20070117805-A1 | Glucocorticoid receptor modulators | PFIZER INC. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117805-A1 | Glucocorticoid receptor modulators | NR3C1, NR3C2, MC2R | NR3C1 1/4885AR 84/4885ESR2 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.