Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286183 | 0.80 | CYP2C19 (0.37) | CYP1A2CYP2D6ESR1CYP2C19GABRA1 | |
| SCHEMBL5865868 | 0.76 | ESR1 (0.48) | CYP1A2CYP2D6ESR1CYP2C19GABRA1 | |
| SCHEMBL3286364 | 0.76 | GABRA1 (0.46) | CYP1A2CYP2D6ESR1GABRA1GABRB2 | |
| SCHEMBL10494911 | 0.76 | CYP2C19 (0.53) | CYP1A2CYP2D6ESR1CYP2C19GABRA1 | |
| SCHEMBL5827515 | 0.73 | ESR1 (0.38) | CYP1A2CYP2D6ESR1CYP2C19GABRA1 | |
| SCHEMBL3285883 | 0.72 | HMGCR (0.38) | ESR1GABRA1GABRB2PDCD1ESR2 | |
| SCHEMBL21635070 | 0.71 | CYP2C19 (0.33) | CYP2C19ALOX15MAPK1HTT | |
| SCHEMBL15000492 | 0.71 | PRKCE (0.47) | CYP1A2CYP2D6ESR1GABRA1GABRB2 | |
| SCHEMBL5571045 | 0.71 | CYP2C19 (0.41) | CYP1A2CYP2D6ESR1CYP2C19GABRA1 | |
| SCHEMBL25865913 | 0.71 | ALOX15 (0.35) | CYP2C19GABRA1GABRB2ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718337-B2 | Electrophotographic photoreceptor | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20090081570-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |
| US-7473507-B2 | Electrophotographic photoreceptor with polyester resin in photosensitive layer | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-01-06 | — | — | US | disclosed |
| US-20060073400-A1 | Electrophotographic photoreceptor | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-04-06 | — | — | US | disclosed |