Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286364 | 0.82 | GABRA1 (0.46) | DHFRESR1PDCD1ESR2CD274 | |
| SCHEMBL3286844 | 0.81 | PTPN1 (0.38) | HMGCRDHFRPRKCIPTPN1PTPN11 | |
| SCHEMBL3287169 | 0.78 | ALOX5 (0.47) | HMGCRPRKCIESR1PDCD1ESR2 | |
| SCHEMBL3823378 | 0.77 | TYR (0.40) | ESR1ALOX5MAOAPTGS2ALOX15 | |
| SCHEMBL8609407 | 0.77 | TYR (0.40) | ESR1ESR2GABRA1GABRB2ALOX5 | |
| SCHEMBL8975468 | 0.77 | ALOX5 (0.44) | HMGCRDHFRPRKCIPTPN1PTPN11 | |
| SCHEMBL1760574 | 0.77 | PTPN1 (0.53) | HMGCRDHFRPRKCIPTPN1PTPN11 | |
| SCHEMBL14135764 | 0.75 | ALDH1A1 (0.38) | PTPN1PTPN11GABRA1GABRB2ALOX12 | |
| SCHEMBL8772337 | 0.75 | ALOX5 (0.45) | ESR1ALOX5PTGS2ALOX15 | |
| SCHEMBL1021760 | 0.75 | AMY1A (0.47) | HMGCRDHFRPRKCIPTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718337-B2 | Electrophotographic photoreceptor | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20090081570-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |
| US-7473507-B2 | Electrophotographic photoreceptor with polyester resin in photosensitive layer | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-01-06 | — | — | US | disclosed |
| US-20060073400-A1 | Electrophotographic photoreceptor | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-04-06 | — | — | US | disclosed |