Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | BAX | Q07812 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135453 | 0.78 | MAOB (0.50) | LTA4HTSHRMAPTKMT2ATDP1 | |
| SCHEMBL3538357 | 0.75 | KDM4E (0.45) | LTA4HTSHRKDM4ENPC1RAB9A | |
| SCHEMBL4801302 | 0.73 | LTA4H (0.45) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL20606107 | 0.71 | — | — | |
| SCHEMBL4144789 | 0.71 | — | — | |
| SCHEMBL303339 | 0.71 | — | — | |
| SCHEMBL224231 | 0.71 | LTA4H (0.46) | LTA4HTSHRMAPTKDM4EMAOA | |
| SCHEMBL9481529 | 0.71 | ADRA2A (0.35) | TSHRKDM4EKMT2A | |
| SCHEMBL1451346 | 0.70 | LTA4H (0.55) | LTA4HTSHRMAPTKDM4EGLA | |
| SCHEMBL76698 | 0.67 | LTA4H (0.50) | LTA4HTSHRMAPTKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714231-B2 | Pyrrolidine GPR40 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-25 | — | — | US | claimed |
| EP-2925741-B1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2016-10-26 | — | — | EP | claimed |
| US-20160280680-A1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2016-09-29 | — | — | US | claimed |
| EP-2925741-A1 | PYRROLIDINE GPR40 MODULATORS | Bristol-Myers Squibb Company (US) | 2015-10-07 | — | — | EP | claimed |
| US-8900725-B2 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO., LTD. | 2014-12-02 | — | — | US | claimed |
| US-8865322-B2 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-10-21 | — | — | US | claimed |
| WO-2014078609-A1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-22 | — | — | WO | claimed |
| EP-2407501-B1 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO LTD (KR) | 2013-09-11 | — | — | EP | claimed |
| EP-2407502-B1 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO LTD (KR) | 2013-06-19 | — | — | EP | claimed |
| US-20120013247-A1 | DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2012-01-19 | — | — | US | claimed |
| US-4743622-A | FLUORO COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-05-10 | — | — | US | claimed |
| US-4694013-A | Insecticidal and acaricidal phenoxypyrdinyl esters and intermediates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-15 | — | — | US | claimed |
| EP-0233834-A1 | Insecticidal trifluormethyl alkane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-08-26 | — | — | EP | claimed |
| EP-0223521-A2 | Insecticidal and acaricidal phenoxypyridinyl esters and intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-27 | — | — | EP | claimed |
| EP-0191723-A1 | Aromatic alkane derivatives, pesticides containing these compounds and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-08-20 | — | — | EP | claimed |
| EP-0179018-A1 | Substituted benzyl ethers, pesticides containing these compounds and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-04-23 | — | — | EP | claimed |
| EP-0136451-A2 | Arylmethyl-ether derivatives, pesticides containing these compounds and process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-04-10 | — | — | EP | claimed |
| EP-0061114-B1 | PHENOXYPYRIDYLMETHYL ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PESTICIDAL COMPOSITIONS | BAYER AG (DE) | 1984-12-12 | — | — | EP | claimed |
| EP-0001399-B1 | PHENOXY-PYRIDINYL-ALCANOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1982-11-10 | — | — | EP | claimed |
| EP-0001399-A1 | Phenoxy-pyridinyl-alcanols, process for their preparation and their use as fungicides | BAYER AG (DE) | 1979-04-18 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120013247-A1 | DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | CLTB, CD40LG, DYNLL2 | LTA4H 1118/4885TSHR 2558/4885MAPT 446/4885 |
| US-20160280680-A1 | PYRROLIDINE GPR40 MODULATORS | GPR55, GPR65, GPR27 | LTA4H 996/4885TSHR 924/4885MAPT 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.