Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328799 | 0.77 | FDPS (0.45) | TAS1R3TAS1R1ALDH1A1LAP3TDP1 | |
| SCHEMBL13431344 | 0.77 | LAP3 (0.54) | LAP3HMGCRTRPA1 | |
| SCHEMBL3712671 | 0.76 | ALDH1A1 (0.39) | TAS1R3TAS1R1ALDH1A1TP53TDP1 | |
| SCHEMBL27490756 | 0.74 | ALDH1A1 (0.46) | TAS1R3TAS1R1ALDH1A1MIFTP53 | |
| SCHEMBL17008447 | 0.74 | ALDH1A1 (0.41) | TAS1R3TAS1R1ALDH1A1TP53CHRNB2 | |
| Potassium SCHEMBL29762014 | 0.72 | ALDH1A1 (0.39) | TAS1R3TAS1R1ALDH1A1TP53CHRNB2 | |
| SCHEMBL546949 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5197835 | 0.69 | ALDH1A1 (0.44) | TAS1R3TAS1R1ALDH1A1TP53CHRNB2 | |
| SCHEMBL14336225 | 0.69 | ALDH1A1 (0.39) | TAS1R3TAS1R1ALDH1A1MIFTP53 | |
| SCHEMBL5007496 | 0.69 | LAP3 (0.43) | LAP3LDHAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404144-B2 | Compositions including polymerizable bisphosphonic acids and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-03-26 | — | — | US | disclosed |
| EP-2407142-A1 | Use of polymerizable bisphosphonic acids for the treatment of tooth surfaces that are not pretreated with phosphoric acid | 3M Innovative Properties Company (US) | 2012-01-18 | — | — | EP | disclosed |
| US-20090075239-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY | 2009-03-19 | — | — | US | disclosed |
| EP-1578377-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M Innovative Properties Company (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20040206932-A1 | Compositions including polymerizable bisphosphonic acids and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2004-10-21 | — | — | US | disclosed |
| WO-2004060327-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |