Naphthalene

Naphthalene

SCHEMBL329188

CC1(C(=O)O)CN1.c1ccc2ccccc2c1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
KMT2A Q03164 6/20 0.39
MEN1 O00255 5/20 0.39
MAPK1 P28482 2/20 0.39
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
EZH2 Q15910 1/20 0.37
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
DAO P14920 1/20 0.36
TSHR P16473 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
AKR1C1 Q04828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5334825 0.69 ALDH1A1 (0.40) GAAMAPTALDH1A1TSHRL3MBTL1
Naphthalene SCHEMBL27548576 0.69 CYP2A6 (0.53) KMT2AMEN1MAPTKDM4EALDH1A1
Naphthalene SCHEMBL28104781 0.69 CYP2A6 (0.53) KMT2AMEN1MAPTKDM4EALDH1A1
Naphthalene SCHEMBL3759523 0.69 CYP2A6 (0.53) KMT2AMEN1MAPTKDM4EALDH1A1
Naphthalene SCHEMBL28769152 0.69 CYP2A6 (0.53) KMT2AMEN1MAPTKDM4EALDH1A1
Naphthalene SCHEMBL263645 0.69 CYP2A6 (0.53) KMT2AMEN1MAPTKDM4EALDH1A1
Naphthalene SCHEMBL28261717 0.69 CYP2A6 (0.53) KMT2AMEN1MAPK1MAPTKDM4E
Naphthalene SCHEMBL1478520 0.68 CYP2A6 (0.61) KMT2AMEN1MAPTKDM4ENPC1
Naphthalene SCHEMBL7201843 0.68 CYP2A6 (0.61) KMT2AMEN1MAPTKDM4ENPC1
Naphthalene SCHEMBL3278833 0.68 CYP2A6 (0.61) KMT2AMEN1MAPTKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256172-B1 Method of treatment and agents useful for same THE UNIVERSITY OF MELBOURNE (AU) 2007-08-14 US claimed
US-7070969-B1 Plasmin inhibitors from the australian brown snake Pseudonaja textilis textilis THE UNIVERSITY OF QUEENSLAND (AU) 2006-07-04 US claimed
EP-4400164-A2 A METHOD OF INDUCING CARDIOMYOCYTES PROLIFERATION AND TREATING HEART DISEASES Yeda Research and Development Co. Ltd (IL) 2024-07-17 EP disclosed
EP-4400174-A2 IMMUNOREGULATORY MOLECULES AND USES THEREFOR The Francis Crick Institute Limited (GB) 2024-07-17 EP disclosed
WO-2024130161-A2 NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF BIONECURE THERAPEUTICS INC (US) 2024-06-20 WO disclosed
US-20240190919-A1 PEPTIDE COMPOUNDS AND THERAPEUTIC USES OF SAME IMMUNITY PHARMA LTD. (IL) 2024-06-13 US disclosed
CN-118146196-A FAP inhibitors 海德堡大学 2024-06-07 CN disclosed
US-20240181020-A1 TREATMENT OF HYPOPARATHYROIDISM ENTERA BIO LTD. (IL) 2024-06-06 US disclosed
US-20240174730-A1 VARIANT FC DOMAINS AND USES THEREOF CIDARA THERAPEUTICS, INC. 2024-05-30 US disclosed
US-11986522-B2 Immunotherapeutic composition and uses thereof ARA VAX PTY LTD (AU) 2024-05-21 US disclosed
US-20240156975-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2024-05-16 US disclosed
WO-1997015663-A1 A NOVEL HAEMOPOIETIN RECEPTOR AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-05-01 WO disclosed
WO-1997012037-A1 A NOVEL HAEMOPOIETIN RECEPTOR AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-04-03 WO disclosed
WO-1997005257-A1 PEPTIDE ANALOG INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1997-02-13 WO disclosed
WO-1997004091-A1 NOVEL RECEPTOR LIGANDS AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-02-06 WO disclosed
EP-0745092-A1 PEPTIDE INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1996-12-04 EP disclosed
EP-0672049-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1995-09-20 EP disclosed
WO-1994028014-A2 PEPTIDE INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1994-12-08 WO disclosed
WO-1994011388-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1994-05-26 WO disclosed
WO-1994003483-A1 ENDOTHELIN RECEPTOR-BINDING COMPOUNDS CHIRON CORPORATION (US) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240181020-A1 TREATMENT OF HYPOPARATHYROIDISM PTH1R, PTMS, CYP24A1 GAA 1716/4885KMT2A 1941/4885MEN1 560/4885
US-20240174730-A1 VARIANT FC DOMAINS AND USES THEREOF FCGR3B, FCGRT, FCGR2A GAA 2219/4885KMT2A 321/4885MEN1 2445/4885
US-20240156975-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A GAA 159/4885KMT2A 4104/4885MEN1 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.