Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | CPT1A | P50416 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | CCR3 | P51677 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5393257 | 0.87 | CCR3 (0.65) | ALDH1A1HTTUSP2TSHRHDAC1 | |
| Hydrochloric Acid SCHEMBL31587217 | 0.87 | USP2 (0.47) | ALDH1A1HTTUSP2TSHRHDAC1 | |
| Hydrochloric Acid SCHEMBL5382308 | 0.86 | CCR3 (0.64) | ALDH1A1HTTUSP2TSHRHDAC1 | |
| SCHEMBL5773446 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HTTUSP2TSHRHDAC1 | |
| SCHEMBL5377302 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HTTUSP2TSHRHDAC1 | |
| SCHEMBL3995292 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HTTUSP2TSHRDRD2 | |
| SCHEMBL17512052 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HTTUSP2TSHRHDAC1 | |
| SCHEMBL16128201 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HTTUSP2TSHRHDAC1 | |
| SCHEMBL13319401 | 0.78 | CYP3A4 (0.54) | ALDH1A1HTTCPT1AFPR2MAPT | |
| SCHEMBL3292500 | 0.78 | CCR3 (0.74) | ALDH1A1HTTHDAC1CPT1ACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723360-B2 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723360-B2 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723360-B2 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1776356-B1 | ALKYL-AND PIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-DERIVATES | BOEHRINGER INGELHEIM INT (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1776356-B1 | ALKYL-AND PIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-DERIVATES | BOEHRINGER INGELHEIM INT (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1776356-A1 | ALKYL-AND PIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-DERIVATES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006013073-A1 | ALKYL-AND PIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-DERIVATES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |
| US-20060030590-A1 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030590-A1 | Alkyl-and piperidine-substituted benzimidazole derivatives | ABCB11, KCNJ11, ABCB1 | ALDH1A1 141/4885HTT 1873/4885USP2 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.