⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534502 | 0.85 | GLS (0.42) | — | |
| SCHEMBL12533563 | 0.81 | GLS (0.47) | — | |
| Terephthalic Acid SCHEMBL5847732 | 0.74 | RARA (0.39) | — | |
| SCHEMBL27671192 | 0.74 | JAK2 (0.36) | — | |
| Bromide SCHEMBL28991986 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL29186840 | 0.73 | — | — | |
| SCHEMBL24773474 | 0.70 | LMNA (0.50) | — | |
| SCHEMBL14084715 | 0.70 | LMNA (0.50) | — | |
| SCHEMBL14084714 | 0.70 | CCNC (0.40) | — | |
| SCHEMBL14510151 | 0.70 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723384-B2 | Keto lactam compounds and use thereof | ABBOTT GMBH & CO. KG. (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20070219182-A1 | Keto Lactam Compounds and Use Thereof | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2007-09-20 | — | — | US | disclosed |
| EP-1692129-A1 | KETO LACTAM COMPOUNDS AND USE THEREOF | Abbott GmbH & Co. KG (DE) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056546-A1 | KETO LACTAM COMPOUNDS AND USE THEREOF | ABBOTT GMBH & CO. KG (DE) | 2005-06-23 | — | — | WO | disclosed |