Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL15320969 | 0.95 | ALOX5 (0.61) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL9525385 | 0.92 | ALOX5 (0.53) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL8228019 | 0.92 | CYP2A6 (0.57) | ALOX5NSD2ABL1PPARGRIN1 | |
| Pyridine SCHEMBL28518713 | 0.92 | ALOX5 (0.53) | ALOX5NSD2ABL1PPARGRIN1 | |
| Hexane SCHEMBL27537617 | 0.92 | ALOX5 (0.53) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL5077381 | 0.89 | ALOX5 (0.50) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL3901006 | 0.88 | NPC1 (0.64) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL29463389 | 0.87 | ALOX5 (0.62) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL707702 | 0.87 | ALOX5 (0.62) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL2489895 | 0.87 | LTA4H (0.51) | ALOX5NSD2ABL1PPARGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137518-A1 | PLATINUM COMPLEXES | Western Sydney University (AU) | 2023-07-27 | — | — | WO | claimed |
| CN-110776454-A | Synthesis method of bufotenine and quaternary ammonium salt thereof and application of bufotenine and quaternary ammonium salt thereof in preparation of analgesic and anti-inflammatory drugs | 马宏跃 | 2020-02-11 | — | — | CN | claimed |
| CN-109761875-A | A kind of new method constructing amido bond | 盐城工学院 | 2019-05-17 | — | — | CN | claimed |
| CN-103923135-B | A kind of deuterated 5-hydroxyl color D-glucosamine glycoside derivates and preparation method thereof | 南京靖龙药物研发有限公司 | 2016-08-31 | — | — | CN | claimed |
| CN-103923135-A | Deuterated 5-hydroxy tryptophan glucoside derivatives and preparation method thereof | NANJING JINGLONG PHARMACEUTICAL RES DEV CO LTD | 2014-07-16 | — | — | CN | claimed |
| US-7420015-B2 | Flame retardant silicone compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-09-02 | — | — | US | claimed |
| CN-1325490-C | Process for preparing high purity hydroxyindolylacetylglyoxylamides | ELBION AG (DE) | 2007-07-11 | — | — | CN | claimed |
| US-7122674-B2 | Process for preparing high-purity hydroxyindolylglyoxylamides | ELBION AG (DE) | 2006-10-17 | — | — | US | claimed |
| EP-1424364-B1 | Flame retardant silicone compositions | SHINETSU CHEMICAL CO (JP) | 2006-09-20 | — | — | EP | claimed |
| CN-1671692-A | Method for producing highly pure hydroxy indolyl glyoxylic acid amides | ELBION AG (DE) | 2005-09-21 | — | — | CN | claimed |
| EP-1525197-A1 | METHOD FOR PRODUCING HIGHLY PURE HYDROXY INDOLYL GLYOXYLIC ACID AMIDES | Elbion AG (DE) | 2005-04-27 | — | — | EP | claimed |
| US-20040106706-A1 | Flame retardant silicone compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | claimed |
| EP-1424364-A1 | Flame retardant silicone compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | claimed |
| US-20040063939-A1 | Process for preparing high-purity hydroxyindolylglyoxylamides | ELBION AG (DE) | 2004-04-01 | — | — | US | claimed |
| WO-2004013127-A1 | METHOD FOR PRODUCING HIGHLY PURE HYDROXY INDOLYL GLYOXYLIC ACID AMIDES | ELBION AG (DE) | 2004-02-12 | — | — | WO | claimed |
| EP-0609010-B1 | A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer | BRIDGESTONE CORP (JP) | 2000-03-15 | — | — | EP | claimed |
| US-5527860-A | PROMOTER IS REACTION PRODUCT OF A SECONDARY AMINE AND ORGANOLITHIUM COMPOUND OR ALCOHOL AND A LITHIUM ALKOXIDE | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-06-18 | — | — | US | claimed |
| EP-0609010-A2 | A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer | BRIDGESTONE CORPORATION (JP) | 1994-08-03 | — | — | EP | claimed |
| JP-6279515-A | — | — | None | — | — | JP | disclosed |
| US-3976639-A | Intermediates for indoles | HOFFMANN-LA ROCHE INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063939-A1 | Process for preparing high-purity hydroxyindolylglyoxylamides | HAAO, HPD, GRHPR | ALOX5 470/4885NSD2 3223/4885ABL1 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.