Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463389 | 1.00 | ALOX5 (0.62) | ALOX5NSD2ABL1PPARGRIN1 | |
| Acetic Acid Methyl Ester SCHEMBL6664145 | 0.88 | APP (0.60) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL329575 | 0.87 | ALOX5 (0.62) | ALOX5NSD2ABL1PPARGRIN1 | |
| Indole SCHEMBL15320969 | 0.86 | ALOX5 (0.61) | ALOX5NSD2ABL1PPARGRIN1 | |
| Ethoxycarbonyl Group SCHEMBL27720865 | 0.86 | APP (0.51) | ALOX5NSD2ABL1PPARGRIN1 | |
| SCHEMBL9265126 | 0.84 | AHR (0.54) | MEN1KMT2APOLBMAPK1APP | |
| SCHEMBL9023367 | 0.84 | MEN1 (0.54) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL31464043 | 0.84 | POLB (0.68) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL18640278 | 0.84 | POLB (0.68) | MEN1KMT2APOLBMAPK1MAPT | |
| SCHEMBL9735601 | 0.82 | MEN1 (0.48) | ALOX5MEN1KMT2APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223273-A2 | COMPOSITIONS AND METHODS FOR MODULATION OF ANTIBODY ACTIVITY | INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) | 2020-11-05 | — | — | WO | claimed |
| US-7122674-B2 | Process for preparing high-purity hydroxyindolylglyoxylamides | ELBION AG (DE) | 2006-10-17 | — | — | US | claimed |
| CN-1275942-C | Benzyloxy substituted indole compound and its analog and their production method and application | UNIV FUDAN (CN) | 2006-09-20 | — | — | CN | claimed |
| US-20040063939-A1 | Process for preparing high-purity hydroxyindolylglyoxylamides | ELBION AG (DE) | 2004-04-01 | — | — | US | claimed |
| EP-3894390-B1 | SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF | HEIDELBERG PHARMA RES GMBH (DE) | 2026-05-20 | — | — | EP | disclosed |
| US-12631644-B2 | Biomarker panel targeted to diseases due to multifactorial ontology of glycocalyx disruption | ARTEREZ, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| US-12599584-B2 | Indoline derivatives, compositions comprising them and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2026-04-14 | — | — | US | disclosed |
| US-12378196-B2 | Synthesis of (S)-6-hydroxytryptophan and derivatives thereof | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2025-08-05 | — | — | US | disclosed |
| US-20250179018-A1 | SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2025-06-05 | — | — | US | disclosed |
| CN-113166057-B | Synthesis of (S) -6-hydroxytryptophan and derivatives thereof | 海德堡医药研究有限责任公司 | 2024-12-31 | — | — | CN | disclosed |
| US-12139459-B2 | Enhancer of fertilization function of sperm | TOHOKU UNIVERSITY (JP) | 2024-11-12 | — | — | US | disclosed |
| US-12071404-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | UCB PHARMA GMBH (DE) | 2024-08-27 | — | — | US | disclosed |
| WO-1993001813-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-02-04 | — | — | WO | disclosed |
| WO-1992014732-A1 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-09-03 | — | — | WO | disclosed |
| EP-0499987-A1 | Platelet activating factor antagonists | ABBOTT LABORATORIES (US) | 1992-08-26 | — | — | EP | disclosed |
| US-5120749-A | Treatment of anaphylactic shock, respiratory distress syndrome, acute inflammation, delayed cellulosr immunity, parturtition, fetal lung maturation, and cellular differentiation | ABBOTT LABORATORIES (US) | 1992-06-09 | — | — | US | disclosed |
| WO-1992004321-A1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-03-19 | — | — | WO | disclosed |
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | disclosed |
| US-4866084-A | EXTRACTED FROM SPONGES | HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. (US) | 1989-09-12 | — | — | US | disclosed |
| CN-87107372-A | Process for preparing 5, 6-dihydroxyindoles and 3-alkyl derivatives and intermediate compounds thereof | — | 1988-08-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063939-A1 | Process for preparing high-purity hydroxyindolylglyoxylamides | HAAO, HPD, GRHPR | ALOX5 470/4885NSD2 3223/4885ABL1 1144/4885 |
| US-12631644-B2 | Biomarker panel targeted to diseases due to multifactorial ontology of glycocalyx disruption | PGF, FGB, LGALS3BP | ALOX5 1412/4885NSD2 4851/4885ABL1 2747/4885 |
| US-12139459-B2 | Enhancer of fertilization function of sperm | CATSPER1, NASP, ZP1 | ALOX5 2382/4885NSD2 3078/4885ABL1 4835/4885 |
| US-12071404-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | GPR17, GPR18, GPR27 | ALOX5 1009/4885NSD2 1552/4885ABL1 2885/4885 |
| US-20250179018-A1 | SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF | AANAT, HNMT, HTR6 | ALOX5 955/4885NSD2 1703/4885ABL1 929/4885 |
| US-12378196-B2 | Synthesis of (S)-6-hydroxytryptophan and derivatives thereof | AANAT, HNMT, HTR6 | ALOX5 695/4885NSD2 1998/4885ABL1 1494/4885 |
| US-12599584-B2 | Indoline derivatives, compositions comprising them and uses thereof | IL6, TNF, IDO1 | ALOX5 163/4885NSD2 4634/4885ABL1 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.