SCHEMBL2502895

SCHEMBL2502895

CO[Si](CN1CCCC1)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
PRMT8 Q9NR22 1/20 0.32
LMNA P02545 1/20 0.32
HRH3 Q9Y5N1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1230677 0.97 HRH3 (0.35) CARM1PRMT6PRMT8LMNAHRH3
SCHEMBL329641 0.97 HRH3 (0.35) CARM1PRMT6PRMT8LMNAHRH3
SCHEMBL1229552 0.80 CSNK2A2 (0.35) LMNA
SCHEMBL776376 0.80 SMN1; SMN2 (0.40) HRH3
SCHEMBL538032 0.78 CYP1A2 (0.35) LMNA
SCHEMBL4069891 0.77
SCHEMBL2383064 0.75 ALDH1A1 (0.30) CARM1PRMT6PRMT8
SCHEMBL1995114 0.75 HRH3 (0.33) CARM1PRMT6PRMT8HRH3
SCHEMBL2508441 0.75 HRH3 (0.33) CARM1PRMT6PRMT8HRH3
SCHEMBL12802639 0.75 HRH3 (0.41) CARM1PRMT6PRMT8HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9637600-B2 Cross-linkable masses based on organosilicon compounds WACKER CHEMIE AG (DE) 2017-05-02 US claimed
US-9637600-B2 Cross-linkable masses based on organosilicon compounds WACKER CHEMIE AG (DE) 2017-05-02 US disclosed
US-9587042-B2 Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-07 US disclosed
CN-102731722-B For the production of the method for modified conjugated diene polymer, modified conjugated diene polymer and polymer composition SUMITOMO CHEMICAL CO., LTD. (JP) 2016-03-16 CN disclosed
CN-102741347-B Curable compositions having improved fire properties HENKEL AG & CO KGAA 2015-06-17 CN disclosed
EP-2789656-B1 Crosslinkable compositions based on organosilicon compounds WACKER CHEMIE AG (DE) 2015-04-22 EP disclosed
US-8987373-B2 Crosslinkable compositions based on organosilicon compounds WACKER CHEMIE AG (DE) 2015-03-24 US disclosed
US-8933165-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-13 US disclosed
US-20140309370-A1 CROSSLINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2014-10-16 US disclosed
EP-2789656-A1 Crosslinkable compositions based on organosilicon compounds Wacker Chemie AG (DE) 2014-10-15 EP disclosed
US-20140088242-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
EP-2367868-B1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2012-11-07 EP disclosed
CN-102731722-A Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL CO 2012-10-17 CN disclosed
US-20120252966-A1 PROCESS FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-10-04 US disclosed
US-20110245377-A1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2011-10-06 US disclosed