Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600376 | 0.85 | EPAS1 (0.40) | EPAS1HSD11B1HTR2AHTR2CCYP1A2 | |
| SCHEMBL27796545 | 0.78 | ALDH1A1 (0.52) | EPAS1HSD11B1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL31619143 | 0.77 | EPAS1 (0.37) | EPAS1NOTUMCYP11B1CYP11B2GPR3 | |
| SCHEMBL24602620 | 0.76 | TSHR (0.47) | CYP1A2CYP2C19ALDH1A1TSHRAHR | |
| SCHEMBL13550065 | 0.74 | RAPGEF4 (0.40) | EPAS1HSD11B1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10776564 | 0.74 | CYP3A4 (0.41) | EPAS1CYP1A2CYP2D6CYP2C19RAB9A | |
| SCHEMBL31611799 | 0.74 | KIF11 (0.47) | ALDH1A1KIF11 | |
| SCHEMBL31303886 | 0.73 | SLC6A4 (0.46) | HSD11B1HTR2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL657298 | 0.73 | SLC6A4 (0.46) | HSD11B1HTR2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7271102 | 0.73 | KIF11 (0.39) | EPAS1HSD11B1HTR2AHTR2CCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100096585-A1 | Process for Preparing 2,6-Dichloro-4-(Trifluoromethyl)Phenylhydrazine Using Mixtures of Dichloro-Fluoro-Trifluoromethylbenzenes | BASF SE (DE) | 2010-04-22 | — | — | US | claimed |
| EP-2137135-A1 | PROCESS FOR PREPARING 2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE USING MIXTURES OF DICHLORO-FLUORO-TRIFLUOROMETHYLBENZENES | BASF SE (DE) | 2009-12-30 | — | — | EP | claimed |
| WO-2008113660-A1 | PROCESS FOR PREPARING 2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE USING MIXTURES OF DICHLORO-FLUORO-TRIFLUOROMETHYLBENZENES | BASF SE (DE) | 2008-09-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100096585-A1 | Process for Preparing 2,6-Dichloro-4-(Trifluoromethyl)Phenylhydrazine Using Mixtures of Dichloro-Fluoro-Trifluoromethylbenzenes | DAZAP1, CYP4Z1, CYP2F1 | EPAS1 3144/4885HSD11B1 813/4885HTR2A 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.