Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | MPL | P40238 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186202 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL2303869 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL30257384 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL1802030 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL131267 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL30257627 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL11480686 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL9833618 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL31378008 | 0.80 | CD274 (0.56) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL543685 | 0.79 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119570524-A | Preparation method of corrosion and scale inhibitor | 淄博凯美可工贸有限公司 | 2025-03-07 | — | — | CN | claimed |
| EP-2350311-B1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | MADRIGAL PHARMACEUTICALS INC (US) | 2013-12-25 | — | — | EP | claimed |
| US-8324385-B2 | Diacylglycerol acyltransferase inhibitors | MADRIGAL PHARMACEUTICALS, INC. (US) | 2012-12-04 | — | — | US | claimed |
| WO-2010056506-A1 | DIACYLGLYCEROL ACLYTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | claimed |
| US-20100113782-A1 | Diacylglycerol Acyltransferase Inhibitors | MADRIGAL PHARMACEUTICALS, INC. | 2010-05-06 | — | — | US | claimed |
| US-6562840-B1 | Non-peptidic inhibitors of proteolytic enzymes such as urokinase | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | claimed |
| EP-1150979-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-11-07 | — | — | EP | claimed |
| US-20010031781-A1 | Heteroaryl amidines, methylamidines and guanidines and use thereof as protease inhibitors | ILLIG CARL R (US) | 2001-10-18 | — | — | US | claimed |
| US-6291514-B1 | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-09-18 | — | — | US | claimed |
| WO-2000047578-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-08-17 | — | — | WO | claimed |
| CN-119570524-B | Preparation method of corrosion and scale inhibitor | 淄博凯美可工贸有限公司 | 2026-03-03 | — | — | CN | disclosed |
| CN-119570524-A | Preparation method of corrosion and scale inhibitor | 淄博凯美可工贸有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119570524-A | Preparation method of corrosion and scale inhibitor | 淄博凯美可工贸有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-115433958-B | Electrochemical synthesis method of 2-aminothiazole compound | 北京工商大学 | 2025-02-21 | — | — | CN | disclosed |
| CN-115466229-B | Para-amidobenzenesulfonyl compound and application thereof | 上海中医药大学 | 2025-01-24 | — | — | CN | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |
| US-4237136-A | IMMUNOSTIMULANTS | GRUNENTHAL GMBH (DE) | 1980-12-02 | — | — | US | disclosed |
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113782-A1 | Diacylglycerol Acyltransferase Inhibitors | DGAT2, DGAT1, MOGAT2 | SMN1; SMN2 4749/4885ALDH1A1 802/4885MAPT 4008/4885 |
| US-20010031781-A1 | Heteroaryl amidines, methylamidines and guanidines and use thereof as protease inhibitors | SERPINE1, PRSS3, PRSS2 | SMN1; SMN2 1864/4885ALDH1A1 3209/4885MAPT 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.