Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609661 | 0.76 | ADORA3 (0.54) | ROCK2ADORA3ADORA2ADYRK1ANFATC1 | |
| SCHEMBL25564874 | 0.75 | ADORA3 (0.49) | ROCK2ADORA3ADORA2ADYRK1ANFATC1 | |
| SCHEMBL25703709 | 0.73 | IDO1 (0.41) | ROCK2ADORA3ADORA2AMAOA | |
| SCHEMBL18253293 | 0.72 | ALKBH5 (0.64) | ROCK2ADORA3ADORA2ADYRK1ANFATC1 | |
| Bauerine C SCHEMBL17867404 | 0.71 | SIRT2 (0.48) | SIRT2DYRK1AMAOAHASPIN | |
| SCHEMBL2770057 | 0.70 | ROCK2 (0.36) | ROCK2ADORA3ADORA2ACYP19A1DYRK1A | |
| SCHEMBL18357365 | 0.70 | GABRP (0.51) | ROCK2ADORA3ADORA2AMAOA | |
| SCHEMBL2628358 | 0.70 | ADORA3 (0.49) | ROCK2ADORA3ADORA2ADYRK1ANFATC1 | |
| SCHEMBL21807233 | 0.69 | ADORA3 (0.42) | ROCK2ADORA3ADORA2ACYP19A1DYRK1A | |
| SCHEMBL24311758 | 0.69 | KDM4E (0.53) | ROCK2CYP19A1DYRK1AMAOAHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| US-20100098788-A1 | Extracts of Curcuma and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2010-04-22 | — | — | US | disclosed |