Bromomethane

Bromomethane

SCHEMBL3305907

CBr.Cc1cc(C)cc(OCC(C)Nc2nc(N)nc(C(C)(C)F)n2)c1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 5/20 0.32
ADRA1D P25100 2/20 0.32
ADRA1A P35348 2/20 0.32
ADRA1B P35368 2/20 0.32
AMD1 P17707 1/20 0.32
TSHR P16473 2/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALOX15 P16050 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SCN9A Q15858 3/20 0.31
LMNA P02545 1/20 0.31
TPH1 P17752 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352185 0.98 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BAMD1
SCHEMBL117903 0.98 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BAMD1
SCHEMBL22188696 0.98 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BAMD1
SCHEMBL14567627 0.88 SCN9A (0.30) SCN9ATPH1
SCHEMBL9240771 0.87 ADRB2 (0.40) HTR7ADRA1DADRA1AADRA1BTSHR
SCHEMBL9066890 0.86 HTR7 (0.32) HTR7ADRA1DADRA1AADRA1BTSHR
SCHEMBL27605123 0.86 LMNA (0.36) HTR7ADRA1DADRA1AADRA1BKDM4E
SCHEMBL6677056 0.85 KDM4E (0.30) KDM4E
SCHEMBL9915543 0.81 LMNA (0.40) HTR7ADRA1DADRA1AADRA1BTSHR
SCHEMBL3433358 0.81 HTR7 (0.39) HTR7ADRA1DADRA1AADRA1BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9060516-B2 Method for controlling aquatic weeds BASF SE (DE) 2015-06-23 US claimed
US-20100093540-A1 Control of submerged aquatic vegitation BASF SE (DE) 2010-04-15 US claimed
WO-2009127635-A1 CONTROL OF SUBMERGED AQUATIC VEGETATION BASF SE (DE) 2009-10-22 WO claimed
US-20090011934-A1 Method for Controlling Aquatic Weeds BASF SE (DE) 2009-01-08 US claimed
EP-1976383-A2 A METHOD FOR CONTROLLING AQUATIC WEEDS BASF SE (DE) 2008-10-08 EP claimed
WO-2007071730-A2 A METHOD FOR CONTROLLING AQUATIC WEEDS BASF SE (DE) 2007-06-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093540-A1 Control of submerged aquatic vegitation CBR3, VAT1, EGLN3 HTR7 4581/4885ADRA1D 1858/4885ADRA1A 2246/4885
US-20090011934-A1 Method for Controlling Aquatic Weeds NOTUM, AQP3, CBR3 HTR7 4327/4885ADRA1D 1261/4885ADRA1A 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.