Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33124 | 0.74 | PGR (0.42) | ESR1PGRPDE4DTBXA2RPTGER4 | |
| SCHEMBL33098 | 0.73 | MAOB (0.43) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL15540220 | 0.72 | MTNR1B (0.50) | PPARDCYP2D6PPARAMTNR1BNQO2 | |
| SCHEMBL15085357 | 0.72 | MTNR1B (0.50) | PPARDCYP2D6PPARAMTNR1BNQO2 | |
| SCHEMBL15927439 | 0.72 | CNR1 (0.42) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL18754774 | 0.72 | CNR2 (0.37) | ESR1CYP2C19CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL9273256 | 0.70 | PPARD (0.48) | PPARDPPARAGRIN2BGRIN1 | |
| SCHEMBL14193158 | 0.70 | KMT2A (0.38) | LMNATSHRMAPK1SMN1; SMN2CYP3A4 | |
| SCHEMBL5468373 | 0.70 | SLC6A2 (0.48) | ESR1LMNACYP2C19CYP2D6CYP3A4 | |
| SCHEMBL32779 | 0.68 | NPC1 (0.49) | LMNAPGRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |