Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29726906 | 0.84 | ALDH1A1 (0.50) | MAPTPOLBKDM4EALDH1A1GFRA3 | |
| SCHEMBL33124 | 0.83 | PGR (0.42) | MAPTPGRPYGLPOLBAPEX1 | |
| SCHEMBL31511361 | 0.82 | CHRNB2 (0.48) | NPC1RAB9AMAPTCHRNB2CHRNA4 | |
| SCHEMBL16499816 | 0.82 | CHRNB2 (0.48) | NPC1RAB9AMAPTCHRNB2CHRNA4 | |
| SCHEMBL15630855 | 0.81 | NPC1 (0.47) | NPC1RAB9AMAPTCHRNA1CHRNG | |
| SCHEMBL25843 | 0.81 | NPC1 (0.44) | NPC1RAB9AMAPTCHRNA1CHRNG | |
| SCHEMBL7476527 | 0.79 | PYGL (0.52) | NPC1RAB9ACHRNB2CHRNA4PYGL | |
| SCHEMBL2575691 | 0.78 | CA12 (0.63) | NPC1RAB9AMAPTCHRNA1CHRNG | |
| SCHEMBL9403350 | 0.77 | OPRM1 (0.56) | MAPTPGRPOLBALDH1A1LMNA | |
| SCHEMBL4312727 | 0.76 | NPC1 (0.42) | NPC1RAB9AMAPTCHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240537-B | Indene oxyacetic acid compound and preparation method and application thereof | 成都阿奇生物医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |