Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32779 | 0.83 | NPC1 (0.49) | PGRGFRA3RETPYGLPOLB | |
| SCHEMBL29726906 | 0.77 | ALDH1A1 (0.50) | GFRA3RETTBXA2RPTGER2POLB | |
| SCHEMBL16499816 | 0.76 | CHRNB2 (0.48) | TBXA2RPTGER4HTTCA12CA1 | |
| SCHEMBL31511361 | 0.76 | CHRNB2 (0.48) | TBXA2RPTGER4HTTCA12CA1 | |
| SCHEMBL33097 | 0.74 | PPARD (0.35) | PGRPDE4DTBXA2RPTGER4ESR1 | |
| SCHEMBL1745471 | 0.74 | SRD5A1 (0.46) | PGRGFRA3RETPYGL | |
| SCHEMBL15970863 | 0.73 | GFRA3 (0.39) | PGRGFRA3RETPYGLTBXA2R | |
| SCHEMBL15970865 | 0.73 | PGR (0.37) | PGRGFRA3RETPYGLTBXA2R | |
| SCHEMBL14514502 | 0.73 | PGR (0.37) | PGRGFRA3RETPYGLTBXA2R | |
| SCHEMBL7442811 | 0.72 | ESR2 (0.54) | PGRRECQLESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |