Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28426250 | 0.77 | CA2 (0.58) | CA2CA4HPGDALDH1A1CA1 | |
| SCHEMBL14411943 | 0.67 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9740762 | 0.67 | CA2 (0.42) | CA2CA4HPGDALDH1A1CA1 | |
| SCHEMBL24573233 | 0.66 | PDE3B (0.33) | ALDH1A1MTNR1AMTNR1BMAPT | |
| SCHEMBL5376710 | 0.66 | ALDH1A1 (0.48) | ALDH1A1MTNR1AMTNR1BNQO2MAPT | |
| SCHEMBL31359703 | 0.65 | CA2 (0.36) | CA2CA4HPGDALDH1A1GRIN2D | |
| SCHEMBL19418758 | 0.65 | ACHE (0.39) | CA2CA4HPGDALDH1A1HSD17B10 | |
| SCHEMBL3155331 | 0.64 | CA2 (0.54) | CA2CA4CA1CA6TSHR | |
| SCHEMBL29726739 | 0.64 | CA2 (0.60) | CA2CA4HPGDALDH1A1CA1 | |
| SCHEMBL9635966 | 0.64 | CA2 (0.60) | CA2CA4HPGDALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100098788-A1 | Extracts of Curcuma and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2010-04-22 | — | — | US | disclosed |