SCHEMBL3310217

SCHEMBL3310217

C=C(C)C(=O)OC(C)CC[Si](O)(O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.35
MTNR1B P49286 2/20 0.35
ELANE P08246 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.33
TSHR P16473 2/20 0.33
MAPT P10636 5/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
MMP12 P39900 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
LMNA P02545 1/20 0.31
XBP1 P17861 1/20 0.31
ATM Q13315 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CTSK P43235 2/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9066682 0.86 MTNR1A (0.34) MTNR1AMTNR1BELANEALDH1A1HPGD
SCHEMBL3310442 0.84 TSHR (0.34) MTNR1AMTNR1BELANEALDH1A1HPGD
SCHEMBL3305043 0.82 ALDH1A1 (0.34) MTNR1AMTNR1BELANEALDH1A1HPGD
SCHEMBL3307216 0.80 ALDH1A1 (0.35) MTNR1AMTNR1BELANEALDH1A1SMN1; SMN2
SCHEMBL15603389 0.77 ALDH1A1 (0.33) ALDH1A1MAPTLMNA
SCHEMBL15949718 0.77 TSHR (0.46) ALDH1A1HPGDTSHRMMP12SMN1; SMN2
SCHEMBL3681972 0.74 LMNA (0.47) ELANEALDH1A1HPGDTSHRNPC1
SCHEMBL16594998 0.73 ALDH1A1 (0.40) MTNR1AMTNR1BELANEALDH1A1TSHR
SCHEMBL2540758 0.73 TSHR (0.50) ALDH1A1TSHRMAPTSMN1; SMN2LMNA
SCHEMBL17891305 0.72 HPGD (0.41) MTNR1AMTNR1BELANEALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1595926-B1 COATING COMPOSITION DAIKIN IND LTD (JP) 2014-03-26 EP disclosed
US-8293840-B2 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2012-10-23 US disclosed
US-7807752-B2 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2010-10-05 US disclosed
US-20100113662-A1 COATING COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
US-20060054053-A1 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2006-03-16 US disclosed
EP-1595926-A1 COATING COMPOSITION Daikin Industries, Ltd. (JP) 2005-11-16 EP disclosed
EP-1153983-B1 Top coating composition NIPPON PAINT CO LTD (JP) 2005-06-15 EP disclosed
EP-1160295-B1 Clear coatings, and method of forming multilayer coatings NIPPON PAINT CO LTD (JP) 2005-06-01 EP disclosed
US-6767984-B2 FILM- FORMING RESIN; SILICATE COMPOUND; HYDROLYZABLE SILYL-CONTAINING RESIN OR GRAFT POLYMER OF THE SILICATE ONTO THE HYDROLYZABLE SILYL-CONTAINING RESIN NIPPON PAINT CO., LTD. (JP) 2004-07-27 US disclosed
EP-0811669-B1 USE OF A FLUORSILICATE AS STAIN-PROOFING AGENT DAIKIN IND LTD (JP) 2004-02-04 EP disclosed
EP-0852251-A1 POLLUTANT DEPOSITION INHIBITOR AND COATING MATERIAL COMPOSITION DAIKIN INDUSTRIES, LIMITED (JP) 1998-07-08 EP disclosed
US-5721015-A CATALYST CURING MAZDA MOTOR CORPORATION (JP) 1998-02-24 US disclosed
EP-0811669-A1 ANTIFOULING AGENT AND NONAQUEOUS COATING COMPOSITION CONTAINING SAID AGENT DAIKIN INDUSTRIES, LIMITED (JP) 1997-12-10 EP disclosed
US-5525673-A LOW-TEMPERATURE CURING AUTOMOBILE TOPCOATS COMPRISING A BLEND OF SILICON-AND FLUORINE-CONTAINING ADDITION POLYMERS; STORAGE-STABLE ONE-PACKAGE; WEATHERPROOFING, WEAR RESISTANCE;ANTISOILANTS KANSAI PAINT COMPANY, LIMITED (JP) 1996-06-11 US disclosed
US-5418293-A Fluoropolymer, epoxy or silicone compound KANSAI PAINT COMPANY, LIMITED (JP) 1995-05-23 US disclosed
US-5408001-A Protective coatings KANSAI PAINT COMPANY, LIMITED (JP) 1995-04-18 US disclosed
US-5387646-A Protective coating; blend of an organosilicon and epoxy polymer KANSAI PAINT COMPANY, LIMITED (JP) 1995-02-07 US disclosed
US-5260376-A Fluoropolymers, hydroxy-polymer, polysiloxanes KANSAI PAINT COMPANY, LIMITED (JP) 1993-11-09 US disclosed
US-5166265-A Protective coatings KANSAI PAINT COMPANY, LIMITED (JP) 1992-11-24 US disclosed
US-5130167-A For automobiles, vinyl polymers containing silicon groups, epoxy groups and hydroxy groups KANSAI PAINT COMPANY, LIMITED (JP) 1992-07-14 US disclosed