Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613866 | 1.00 | CYP3A4 (0.35) | CYP3A4TDP1TAAR1SLC6A2MAOA | |
| SCHEMBL613867 | 1.00 | CYP3A4 (0.35) | CYP3A4TDP1TAAR1SLC6A2MAOA | |
| SCHEMBL7196495 | 0.98 | CYP3A4 (0.33) | CYP3A4TDP1TAAR1SLC6A2MAOA | |
| SCHEMBL828451 | 0.98 | CYP3A4 (0.33) | CYP3A4TDP1TAAR1SLC6A2MAOA | |
| SCHEMBL5177211 | 0.98 | CYP3A4 (0.33) | CYP3A4TDP1TAAR1SLC6A2MAOA | |
| Hydrochloric Acid SCHEMBL4527827 | 0.96 | CYP3A4 (0.32) | CYP3A4TDP1TAAR1 | |
| Hydrochloric Acid SCHEMBL7834687 | 0.96 | CYP3A4 (0.32) | CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL9740749 | 0.96 | CYP3A4 (0.32) | CYP3A4TDP1TAAR1 | |
| Hydrochloric Acid SCHEMBL4527828 | 0.96 | CYP3A4 (0.32) | CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL10627872 | 0.96 | CYP3A4 (0.32) | CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710422-B1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-07 | — | — | EP | disclosed |
| CN-111417618-B | Process for preparing enantiomerically and diastereomerically enriched cyclobutane amines and amides | 先正达参股股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-11053188-B2 | Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-06 | — | — | US | disclosed |
| EP-3489213-B1 | COMPOSITION FOR USE IN A METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2021-04-28 | — | — | EP | disclosed |
| US-20200407311-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-31 | — | — | US | disclosed |
| EP-3710422-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES | Syngenta Participations AG (CH) | 2020-09-23 | — | — | EP | disclosed |
| US-10752625-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | SCIFLUOR LIFE SCIENCES, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190194195-A1 | METHOD OF MAKING TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID COMPOUNDS | FELIQS CORPORATION (JP) | 2019-06-27 | — | — | US | disclosed |
| US-10253025-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | SCIFLUOR LIFE SCIENCES, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| EP-3233778-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2019-02-20 | — | — | EP | disclosed |
| WO-2007082927-A1 | CHEMICAL TRANSFORMATION PROCESS IN THE PRESENCE OF A RUTHENIUM CATALYST | BASF SE (DE) | 2007-07-26 | — | — | WO | disclosed |
| EP-1567535-B1 | BIDENTATE C,P CHIRAL PHOSPHINE LIGANDS | HOFFMANN LA ROCHE (CH) | 2007-01-17 | — | — | EP | disclosed |
| US-7144897-B2 | Hydroxy alkyl amines | Elan Oharmaceuticals, Inc. (US) | 2006-12-05 | — | — | US | disclosed |
| US-20050130936-A1 | Processes and intermediates for preparing benzyl epoxides | PHARMACIA & UPJOHN COMPANY | 2005-06-16 | — | — | US | disclosed |
| US-6849750-B2 | Processes and intermediates for preparing benzyl epoxides | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040044072-A1 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY | 2004-03-04 | — | — | US | disclosed |
| US-20030166717-A1 | Hydroxy alkyl amines | FRESKOS JOHN (US) | 2003-09-04 | — | — | US | disclosed |
| US-20030004360-A1 | Processes and intermediates for preparing benzyl epoxides | PHARMACIA & UPJOHN COMPANY | 2003-01-02 | — | — | US | disclosed |
| US-5780692-A | CATALYTIC ASYMMETRIC HYDROGENATION OF A BENZOPHENONE; SIMPLIFICATION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0781749-A2 | Process for producing optically active benzhydrol compounds | Takasago International Corporation (JP) | 1997-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194195-A1 | METHOD OF MAKING TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID COMPOUNDS | NISCH, SLC10A1, AANAT | CYP3A4 346/4885TDP1 1783/4885TAAR1 655/4885 |
| US-20030166717-A1 | Hydroxy alkyl amines | PSEN1, MAOA, PSEN2 | CYP3A4 879/4885TDP1 189/4885TAAR1 125/4885 |
| US-20040044072-A1 | Substituted hydroxyethylamines | BACE1, BACE2, PSEN1 | CYP3A4 737/4885TDP1 257/4885TAAR1 1706/4885 |
| US-20050130936-A1 | Processes and intermediates for preparing benzyl epoxides | CYP2F1, VKORC1, POR | CYP3A4 12/4885TDP1 4153/4885TAAR1 4237/4885 |
| US-10752625-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | NISCH, SLC10A1, AANAT | CYP3A4 346/4885TDP1 1783/4885TAAR1 655/4885 |
| US-20030004360-A1 | Processes and intermediates for preparing benzyl epoxides | CYP2F1, VKORC1, VKORC1L1 | CYP3A4 14/4885TDP1 3808/4885TAAR1 3711/4885 |
| US-20200407311-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES | TBCB, ADORA2B, ADRA2B | CYP3A4 418/4885TDP1 4095/4885TAAR1 474/4885 |
| US-10253025-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | NISCH, SLC10A1, AANAT | CYP3A4 346/4885TDP1 1783/4885TAAR1 655/4885 |
| US-11053188-B2 | Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides | TBCB, ADORA2B, CCNB3 | CYP3A4 519/4885TDP1 3996/4885TAAR1 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.