SCHEMBL331031

SCHEMBL331031

CCOC(=O)CC(SP(=O)(OC)OC)C(=O)OCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
ALOX15 P16050 3/20 1.00
CYP3A4 P08684 2/20 1.00
TSHR P16473 2/20 1.00
TDP1 Q9NUW8 1/20 1.00
CHRM1 P11229 1/20 0.69
ADORA1 P30542 1/20 0.69
HSD17B10 Q99714 1/20 0.69
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
TRPA1 O75762 1/20 0.34
KDM4E B2RXH2 3/20 0.33
CYP2D6 P10635 2/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11215746 1.00 ALDH1A1 (1.00) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL12211313 0.92 ALDH1A1 (0.85) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL12211315 0.92 ALDH1A1 (0.85) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL715694 0.83 ALDH1A1 (0.70) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL10109640 0.83 ALDH1A1 (0.70) ALDH1A1ALOX15CYP3A4TSHRTDP1
Malathion SCHEMBL3705116 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15CYP3A4TSHRTDP1
Malathion SCHEMBL124812 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15CYP3A4TSHRTDP1
Malathion SCHEMBL27358 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL10148165 0.81 ALDH1A1 (0.68) ALDH1A1ALOX15CYP3A4TSHRTDP1
Malathion SCHEMBL21693725 0.81 ALDH1A1 (0.97) ALDH1A1ALOX15CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186608-A1 NANODIAMONDS AS DELIVERY PLATFORM FOR OXIME ANTIDOTES TO CENTRAL NERVOUS SYSTEM IN ORGANOPHOSPHATE POISONING TALLINN UNIVERSITY OF TECHNOLOGY (EE) 2025-06-12 US claimed
US-20240102976-A1 METHOD FOR SCREENING PESTICIDE RESIDUES IN MEDICINE FOOD HOMOLOGY CHARACTERISTIC AGRICULTUREAL PRODUCTS CHANGCHUN CUSTOMS TECHNOLOGY CENTER (CN) 2024-03-28 US claimed
WO-2020081765-A1 METHOD AND KIT FOR PESTICIDES DETECTION, AND PLASMID, BACULOVIRUS, CELL AND METHOD OF PREPARING THE SAME FOR PESTICIDES DETECTION ACADEMIA SINICA (TW) 2020-04-23 WO claimed
CN-110618218-A Analysis method for rapidly screening pesticide and metabolite residues in tea 国家地质实验测试中心 2019-12-27 CN claimed
US-10167498-B1 Gradient elution moving boundary electrophoresis for use with complex samples and detection of toxins APPLIED RES ASSOCIATES INC (US) 2019-01-01 US claimed
CN-106918656-A A kind of 153 kinds of methods of residues of pesticides in detection Yixinfumai particle 天士力制药集团股份有限公司 2017-07-04 CN claimed
EP-3030084-A2 ORGANOPHOSPHATES FOR TREATING AFFLICTIONS OF THE SKIN Attillaps Holdings (US) 2016-06-15 EP claimed
CN-102680589-B Method for determining pesticide residue in ginseng by liquid chromatography-tandem mass spectrometry SHANGHAI INSTITUTE FOR FOOD AND DRUG CONTROL (CN) 2015-12-02 CN claimed
US-20150158893-A1 PROCESS FOR PREPARING MALATHION FOR PHARMACEUTICAL USE TARO PHARMACEUTICALS NORTH AMERICA, INC. (KY) 2015-06-11 US claimed
US-20150086596-A1 ORGANOPHOSPHATES FOR TREATING AFFLICTIONS OF THE SKIN ATTILLAPS HOLDINGS 2015-03-26 US claimed
US-20070010496-A1 Process for Preparing Malathion for Pharmaceutical Use TARO PHARMACEUTICALS INDUSTRIES LTD. (IL) 2007-01-11 US claimed
WO-2006017263-A9 TOPICAL GEL FORMULATION COMPRISING ORGANOPHOSPHATE INSECTICIDE AND ITS PREPARATION THEREOF TARO PHARMA IND (IL) 2006-06-01 WO claimed
US-20060084632-A1 Topical gel formulation comprising organophosphate insecticide and its preparation thereof TARO PHARMACEUTICALS NORTH AMERICA, INC. (KY) 2006-04-20 US claimed
WO-2006017263-A1 TOPICAL GEL FORMULATION COMPRISING ORGANOPHOSPHATE INSECTICIDE AND ITS PREPARATION THEREOF TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) 2006-02-16 WO claimed
EP-1392825-A4 PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 COMMW SCIENT IND RES ORG (AU) 2005-01-26 EP claimed
US-20040161818-A1 Phosphotriesterase from agrobacterium radiobacter p230 COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-08-19 US claimed
CN-1509329-A Phosphotriesterase from Agrobacterium radiobacter P230 �����ѧ�����о���֯ 2004-06-30 CN claimed
EP-1392825-A1 PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-03-03 EP claimed
WO-2002092803-A1 PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2002-11-21 WO claimed
WO-1992021779-A1 DETECTION OF PESTICIDES OF THE ORGANOPHOSPHORUS AND/OR CARBAMATE FAMILY ANADIAG (FR) 1992-12-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150158893-A1 PROCESS FOR PREPARING MALATHION FOR PHARMACEUTICAL USE MSMO1, DDO, DCPS ALDH1A1 1780/4885ALOX15 401/4885CYP3A4 55/4885
US-20040161818-A1 Phosphotriesterase from agrobacterium radiobacter p230 PPA1, PHPT1, DPY30 ALDH1A1 1959/4885ALOX15 4074/4885CYP3A4 381/4885
US-20250186608-A1 NANODIAMONDS AS DELIVERY PLATFORM FOR OXIME ANTIDOTES TO CENTRAL NERVOUS SYSTEM IN ORGANOPHOSPHATE POISONING ACHE, BCHE, DDT ALDH1A1 1912/4885ALOX15 4856/4885CYP3A4 24/4885
US-20070010496-A1 Process for Preparing Malathion for Pharmaceutical Use MSMO1, DDO, DCPS ALDH1A1 1780/4885ALOX15 401/4885CYP3A4 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.